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MIR98 and PLOD1
Data Source:
BioGRID
(unspecified method)
MIR98
PLOD1
Description
microRNA 98
procollagen-lysine,2-oxoglutarate 5-dioxygenase 1
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Extracellular Space
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Rough Endoplasmic Reticulum Membrane
Extracellular Exosome
Catalytic Complex
Molecular Function
MRNA 3'-UTR Binding
MRNA Binding Involved In Posttranscriptional Gene Silencing
Iron Ion Binding
Protein Binding
Procollagen-lysine 5-dioxygenase Activity
L-ascorbic Acid Binding
Procollagen Glucosyltransferase Activity
Biological Process
Negative Regulation Of Cell Population Proliferation
Negative Regulation Of Gene Expression
Negative Regulation Of Extracellular Matrix Disassembly
Negative Regulation Of Interleukin-1 Beta Production
Negative Regulation Of Interleukin-10 Production
Negative Regulation Of Interleukin-6 Production
Negative Regulation Of Interleukin-8 Production
Negative Regulation Of Tumor Necrosis Factor Production
Gene Silencing By MiRNA
MiRNA Mediated Inhibition Of Translation
Negative Regulation Of Tyrosine Phosphorylation Of STAT Protein
Positive Regulation Of Neuron Apoptotic Process
Interleukin-6-mediated Signaling Pathway
Negative Regulation Of Interleukin-6-mediated Signaling Pathway
Regulation Of Cytokine Production Involved In Inflammatory Response
Negative Regulation Of Cytokine Production Involved In Inflammatory Response
Cellular Response To Amyloid-beta
Negative Regulation Of Vascular Endothelial Cell Proliferation
Response To Hypoxia
Protein O-linked Glycosylation
Epidermis Development
Peptidyl-lysine Hydroxylation
Protein Phosphopantetheinylation
Pathways
Collagen biosynthesis and modifying enzymes
Drugs
Ascorbic acid
Diseases
Ehlers-Danlos syndrome (EDS), including: EDS classical type (EDS1/2); EDS hypermobility type (EDS3); EDS vascular type (EDS4); EDS kyphoscoliosis type (EDS6); EDS arthrochalasia type (EDS7A/7B); EDS dermatospraxis type (EDS7C); EDS autosomal recessive cardiac valvular form (EDSCV); EDS musculocontractural type (EDSMC); EDS progeroid form (EDSP); Tenascin-X deficiency (TNXD); Brittle cornea syndrome (EDS6B); EDS-like spondylocheiro dysplasia (SCD-EDS)
Nevo syndrome
GWAS
Bipolar disorder (
31043756
)
Diastolic blood pressure x alcohol consumption interaction (2df test) (
29912962
)
Moyamoya disease (
29273593
)
Platelet count (
27863252
)
Plateletcrit (
27863252
)
Tuberculosis (
29036319
)
Interacting Genes
77 interacting genes:
ADARB1
APOBEC3B
ATXN2L
C1QBP
CPSF1
DARS1
DDX1
DDX21
DDX3X
DDX3Y
DHX36
EDC4
EIF2AK2
EPRS1
ESRP1
FAM98A
FUS
G3BP2
GRSF1
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IARS1
IGF2BP1
IGF2BP2
IGF2BP3
KNOP1
LARP7
LARS1
LIN28A
LIN28B
LRPPRC
MARS1
MATR3
MSI1
MSI2
NOL6
NONO
NUDT16L1
NUFIP2
PDCD11
PLOD1
PTBP1
PTBP3
PUM1
QARS1
RARS1
RBM12B
RBM14
RTCB
SAFB
SF3B1
SF3B2
SF3B3
SFPQ
STRBP
SYNCRIP
TAF15
TRA2A
TRA2B
TRIM25
TUT4
U2SURP
UPF1
YBX1
YBX3
ZFR
ZNF346
40 interacting genes:
MIR1-2
MIR10B
MIR122
MIR128-2
MIR141
MIR143
MIR15A
MIR15B
MIR17
MIR18A
MIR18B
MIR199A2
MIR19A
MIR19B1
MIR206
MIR20A
MIR214
MIR221
MIR222
MIR29B1
MIR34A
MIR34B
MIR363
MIR7-2
MIR7-3
MIR9-1
MIR9-2
MIR98
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
USP4
Entrez ID
407054
5351
HPRD ID
01086
Ensembl ID
ENSG00000271886
ENSG00000083444
Uniprot IDs
Q02809
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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