CD180 and ADAMTS6

Data Source:
BioGRID (proximity labelling technology)

		CD180	ADAMTS6
Description		CD180 molecule	ADAM metallopeptidase with thrombospondin type 1 motif 6
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Plasma Membrane Integral Component Of Membrane Extracellular Matrix	Extracellular Matrix
	Molecular Function	Protein Binding	Metalloendopeptidase Activity Metallopeptidase Activity Metal Ion Binding
	Biological Process	B Cell Proliferation Involved In Immune Response Inflammatory Response Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway Innate Immune Response Cellular Response To Lipopolysaccharide	Kidney Development Cardiac Septum Development Proteolysis Extracellular Matrix Organization Aorta Development Coronary Vasculature Development
Pathways		Toll Like Receptor 4 (TLR4) Cascade	Defective B3GALTL causes Peters-plus syndrome (PpS) O-glycosylation of TSR domain-containing proteins
Drugs
Diseases
GWAS		Common carotid intima-media thickness in HIV infection ( 29206233) General cognitive ability ( 29844566) Gut microbiota (bacterial taxa) ( 27723756)	Brain morphology (MOSTest) ( 32665545) Central corneal thickness ( 32528159 31798171 29760442) Corneal structure ( 23291589) Corpus callosum anterior volume ( 31530798) Cortical surface area (MOSTest) ( 32665545) Feeling tense ( 29500382) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Heel bone mineral density ( 30598549) Height ( 31562340) Inguinal hernia ( 26686553) Intraocular pressure ( 29617998 29785010 30054594) Non-response to bupropion and depression ( 27622933) Osteosarcoma ( 23727862) Schizophrenia ( 23212062) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		1 interacting genes: LY86	1 interacting genes: SNTA1
Entrez ID		4064	11174
HPRD ID		03749	05421
Ensembl ID		ENSG00000134061	ENSG00000049192
Uniprot IDs		Q99467	Q5IR90 Q9UKP5
PDB IDs		3B2D
Enriched GO Terms of Interacting Partners?
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