ARL3 and RP2

Data Source:
BioGRID (pull down, pull down)
HPRD (in vivo, in vitro)

		ARL3	RP2
Description		ADP ribosylation factor like GTPase 3	RP2 activator of ARL3 GTPase
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Centrosome Spindle Microtubule Cytoplasmic Microtubule Cilium Microtubule Cytoskeleton Midbody Photoreceptor Connecting Cilium Extracellular Exosome	Nucleoplasm Cytoplasm Golgi Apparatus Centriole Plasma Membrane Cilium Nuclear Body Cytoplasmic Vesicle Ciliary Basal Body Extracellular Exosome Periciliary Membrane Compartment
	Molecular Function	Magnesium Ion Binding GTPase Activity Protein Binding GTP Binding Microtubule Binding GDP Binding GTPase Activating Protein Binding	Magnesium Ion Binding GTPase Activator Activity Protein Binding GTP Binding Unfolded Protein Binding
	Biological Process	Mitotic Cytokinesis Kidney Development Post-Golgi Vesicle-mediated Transport Golgi To Plasma Membrane Transport Smoothened Signaling Pathway Small GTPase Mediated Signal Transduction Intraciliary Transport Photoreceptor Cell Development Cilium Assembly Protein Localization To Cilium Protein Localization To Ciliary Membrane	Cell Morphogenesis Protein Folding Post-Golgi Vesicle-mediated Transport Post-chaperonin Tubulin Folding Pathway Visual Perception Protein Transport Positive Regulation Of GTPase Activity
Pathways		Trafficking of myristoylated proteins to the cilium	Trafficking of myristoylated proteins to the cilium
Drugs		2-(N-morpholino)ethanesulfonic acid Guanosine-5'-Diphosphate
Diseases			Retinitis pigmentosa (RP)
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 30072576) Brain morphology (MOSTest) ( 32665545) Diastolic blood pressure ( 30487518) Mean arterial pressure ( 30487518) Mean arterial pressure (long-term average) ( 28348047) Prostate cancer ( 23535732) Pulse pressure ( 30487518) Refractive error ( 32231278) Schizophrenia ( 28991256 25056061 27922604) Systolic blood pressure ( 30487518) Systolic blood pressure (long-term average) ( 28348047) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		11 interacting genes: ARL2BP GOLGA4 LRIF1 PDE6D RP2 TBL1X TLE1 TP53 TUBA1A UBR1 UNC119	3 interacting genes: ARL3 OSTF1 PM20D2
Entrez ID		403	6102
HPRD ID		05260	02424
Ensembl ID		ENSG00000138175	ENSG00000102218
Uniprot IDs		P36405	A0A1B2JLU2 O75695
PDB IDs			2BX6 3BH6 3BH7
Enriched GO Terms of Interacting Partners?
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