VMAC and TFAP4

Data Source:
BioGRID (two hybrid)

		VMAC	TFAP4
Description		vimentin type intermediate filament associated coiled-coil protein	transcription factor AP-4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Type III Intermediate Filament	Chromatin Nucleus Nucleoplasm Mitochondrion Transcription Repressor Complex
	Molecular Function	Protein Binding	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Protein Homodimerization Activity Histone Deacetylase Binding Sequence-specific DNA Binding E-box Binding Sequence-specific Double-stranded DNA Binding
	Biological Process		Regulation Of Transcription By RNA Polymerase II DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator Negative Regulation Of Cell Population Proliferation Positive Regulation Of Apoptotic Process Negative Regulation Of DNA Binding Negative Regulation By Host Of Viral Transcription Positive Regulation By Host Of Viral Transcription Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Protein-containing Complex Assembly Negative Regulation Of Cell Cycle Arrest Cellular Response To Dexamethasone Stimulus Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Post bronchodilator FEV1/FVC ratio ( 26634245)	Brain morphology (MOSTest) ( 32665545) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Lung function (FEV1/FVC) ( 26635082) Platelet count ( 32888494) Prostate-specific antigen levels ( 28139693)
Interacting Genes		16 interacting genes: BANP KANK2 LMO2 LMO3 LMO4 LNX1 NGLY1 PPP1R32 PSMA1 SCNM1 SDK2 SPG21 TFAP4 ZBTB25 ZNF326 ZNF80	12 interacting genes: AJUBA EXOSC8 GOLGA2 INCA1 MCRS1 PDE9A PTPN3 SFMBT2 TEKT4 TRAF1 TRAF4 VMAC
Entrez ID		400673	7023
HPRD ID		18623	11795
Ensembl ID		ENSG00000187650	ENSG00000090447
Uniprot IDs		Q2NL98	Q01664
PDB IDs
Enriched GO Terms of Interacting Partners?
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