SERTM1 and GJB1

Data Source:
BioGRID (two hybrid)

		SERTM1	GJB1
Description		serine rich and transmembrane domain containing 1	gap junction protein beta 1
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane Intracellular Membrane-bounded Organelle	Endoplasmic Reticulum Membrane Connexin Complex Integral Component Of Membrane
	Molecular Function	Protein Binding	Gap Junction Channel Activity Protein Binding
	Biological Process		Cell-cell Signaling Nervous System Development Gap Junction Assembly Transmembrane Transport
Pathways			Oligomerization of connexins into connexons Oligomerization of connexins into connexons Transport of connexins along the secretory pathway Gap junction assembly
Drugs
Diseases			Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
GWAS		Cocaine dependence ( 31212010) Nickel levels ( 26025379) Urinary albumin excretion ( 32277301)
Interacting Genes		14 interacting genes: APP CD53 CLDN7 EMP1 GJB1 GPR42 GPX8 KCNJ6 LHFPL5 LRRC4C MS4A4A MTIF3 SPACA1 TMEM19	57 interacting genes: APOL3 APP BMP10 C1GALT1 C2CD2L C3orf52 CALM1 CD37 CD79A CDIPT CLEC7A CMTM3 CMTM5 CNST COMT CTXN3 CXCL9 EFNA5 EGFR EMP3 EPHA1 GJB2 GLP1R GPR25 IER3IP1 ITGAM LAT LHFPL2 MAL MAL2 MFF MS4A13 MST1R NDUFB11 NIPAL4 PRKACA PRKCA PTPN2 PTPN9 RTP2 SCD SERTM1 SLC12A7 SRC STX8 TEX264 TF TM4SF4 TMEM120B TMEM14C TMEM19 TMEM218 TMEM98 UPK1B VEGFA VKORC1 YIPF6
Entrez ID		400120	2705
HPRD ID		14219	02367
Ensembl ID		ENSG00000180440	ENSG00000169562
Uniprot IDs		A2A2V5	A0A654ICJ7 P08034
PDB IDs			1TXH 5KK9
Enriched GO Terms of Interacting Partners?
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