LAIR1 and CNOT3

Data Source:
HPRD (two hybrid)

		LAIR1	CNOT3
Description		leukocyte associated immunoglobulin like receptor 1	CCR4-NOT transcription complex subunit 3
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GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Specific Granule Membrane Tertiary Granule Membrane	P-body Nucleus Cytosol CCR4-NOT Complex CCR4-NOT Core Complex
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Adaptive Immune Response Neutrophil Degranulation Regulation Of Immune Response	Nuclear-transcribed MRNA Poly(A) Tail Shortening Trophectodermal Cell Differentiation Regulation Of Transcription, DNA-templated Regulation Of Translation DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Gene Silencing By RNA Positive Regulation Of Cold-induced Thermogenesis Regulation Of Stem Cell Population Maintenance
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Neutrophil degranulation	Deadenylation of mRNA TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain
Drugs
Diseases
GWAS			PEG-asparaginase hypersensitivity without enzyme activity in childhood acute lymphoblastic leukaemia ( 30450575)
Interacting Genes		4 interacting genes: APP CSK PTPN11 PTPN6	8 interacting genes: CAND1 CAND2 CNOT1 CNOT2 CNOT4 CNOT8 CREBBP ID3
Entrez ID		3903	4849
HPRD ID		04292	05368
Ensembl ID		ENSG00000167613	ENSG00000088038
Uniprot IDs		A8MZ84 D3YTC8 Q6GTX8	A0A024R4R3 O75175
PDB IDs		3KGR 3RP1	4C0D 4C0G 5FU6 5FU7
Enriched GO Terms of Interacting Partners?
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