CNOT3

Description		CCR4-NOT transcription complex subunit 3
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GO Annotations	Cellular Component	P-body Nucleus Cytosol CCR4-NOT Complex CCR4-NOT Core Complex
	Molecular Function	Protein Binding
	Biological Process	Nuclear-transcribed MRNA Poly(A) Tail Shortening Trophectodermal Cell Differentiation Regulation Of Transcription, DNA-templated Regulation Of Translation DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Gene Silencing By RNA Positive Regulation Of Cold-induced Thermogenesis Regulation Of Stem Cell Population Maintenance
Pathways		Deadenylation of mRNA TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain
Drugs
Diseases
GWAS		PEG-asparaginase hypersensitivity without enzyme activity in childhood acute lymphoblastic leukaemia ( 30450575)
Novel Interacting Genes		1 novel interacting genes: LAIR1
Interacting Genes		8 interacting genes: CAND1 CAND2 CNOT1 CNOT2 CNOT4 CNOT8 CREBBP ID3
Entrez ID		4849
HPRD ID		05368
Ensembl ID		ENSG00000088038
Uniprot IDs		A0A024R4R3 O75175
PDB IDs		4C0D 4C0G 5FU6 5FU7
Enriched GO Terms of Interacting Partners?
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