REP15 and EVI5

Data Source:
BioGRID (two hybrid)

		REP15	EVI5
Description		RAB15 effector protein	ecotropic viral integration site 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endosome Membrane Early Endosome Membrane Perinuclear Region Of Cytoplasm Recycling Endosome	Nucleus Microtubule Organizing Center Spindle Cytosol
	Molecular Function	Protein Binding	GTPase Activator Activity Protein Binding Small GTPase Binding
	Biological Process	Receptor Recycling Transferrin Transport	Intracellular Protein Transport Cell Cycle Retrograde Transport, Endosome To Golgi Positive Regulation Of GTPase Activity Cell Division Activation Of GTPase Activity Regulation Of Cilium Assembly
Pathways
Drugs
Diseases
GWAS			Allergic disease (asthma, hay fever or eczema) ( 29785011) Apolipoprotein B levels ( 32203549) Asthma or allergic disease (pleiotropy) ( 29785011) Cholesterol, total ( 24097068 25961943 20686565) Epstein Barr virus nuclear antigen 1 IgG levels or multiple sclerosis ( 26819262) LDL cholesterol ( 30275531 25961943) LDL cholesterol levels ( 32203549) Low density lipoprotein cholesterol levels ( 32154731) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 27863252) Monocyte percentage of white cells ( 32888494 27863252) Multiple sclerosis ( 31604244 24076602 19525955 21833088 27386562) Systemic lupus erythematosus ( 28714469) Total cholesterol levels ( 28334899 30275531)
Interacting Genes		5 interacting genes: ARID3A EVI5 GNG11 ZRSR2 ZRSR2P1	22 interacting genes: ARL4A AURKB BIRC5 CCDC185 CEP19 CSNK1D ELOA FAM161A FBXO5 IMP3 INCENP LENG1 LMO1 MB21D2 MCRS1 MORF4L2 PRPF31 REP15 STX3 TCEANC TNFAIP8L1 ZNF446
Entrez ID		387849	7813
HPRD ID		18804	04249
Ensembl ID		ENSG00000174236	ENSG00000067208
Uniprot IDs		Q6BDI9	O60447 Q59FE7
PDB IDs
Enriched GO Terms of Interacting Partners?
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