KRTAP10-9 and FARS2

Data Source:
BioGRID (two hybrid, two hybrid)

		KRTAP10-9	FARS2
Description		keratin associated protein 10-9	phenylalanyl-tRNA synthetase 2, mitochondrial
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Keratin Filament	Cytoplasm Mitochondrion Mitochondrial Matrix
	Molecular Function	Protein Binding	TRNA Binding Phenylalanine-tRNA Ligase Activity Protein Binding ATP Binding
	Biological Process	Keratinization	TRNA Aminoacylation For Protein Translation Phenylalanyl-tRNA Aminoacylation TRNA Processing
Pathways		Keratinization	Mitochondrial tRNA aminoacylation
Drugs			Phenylalanine
Diseases
GWAS			Change in glucose in response to thiazide diuretic treatment in hypertension ( 29523524) Copper levels ( 26025379) Height ( 28552196) JT interval (sulfonylurea treatment interaction) ( 27958378) Metabolite levels ( 23823483) Obesity (early onset extreme) ( 23563609) Subjective response to placebo treatment in childhood asthma (change in cough/wheeze) ( 31557306)
Interacting Genes		226 interacting genes: ADAMTSL4 ALDH3B1 ALPI ANKS1A ARFGAP1 ATXN7L1 AVPI1 BCL6B BMP7 BRME1 C10orf62 C11orf87 C22orf39 C5orf60 CATIP CATSPER1 CBX2 CCDC26 CD300LG CDKL3 CHIC2 CHRD CHRNG CKS1B CLK4 CNNM3 CRCT1 CREB5 CST9L CXCL16 CYSRT1 DHRS1 DHX57 DMRT3 DOCK2 EIF4E2 EZH2 FAM124B FAM161A FAM74A4 FAM76B FARS2 FBXW5 GABARAPL1 GABARAPL2 GATA2 GLIDR GLP1R GLRX3 GNE GPATCH2L GSTP1 GUCD1 HBG1 HBZ HCK HES6 HOXA1 HOXB9 HOXC8 HPCAL1 HSBP1 HSD3B7 IGSF8 INPP5D IQUB ITGB4 ITGB5 KAT5 KIAA0040 KIF9 KLHL38 KRT20 KRT83 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP12-1 KRTAP12-3 KRTAP26-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP5-11 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-4 LCE1A LCE1B LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A LUZP4 MAB21L3 MAPKBP1 MAZ MED30 MEOX2 MOBP MT1DP MXI1 MYPOP NAXD NBPF19 NECTIN3 NKD1 NOTCH2NLA NPBWR2 NPDC1 NPPB NR1D2 NUFIP2 OTX1 PCSK5 PDE9A PDGFRB PGAP2 PGLS PIGS PIN1 PLSCR1 POU4F2 PRKAA2 PRKAB2 PRPF31 PTGER3 PTPMT1 PVR RAB7A RASD1 RHNO1 RSPO2 SCARB1 SCNM1 SEMA3B SHFL SLC23A1 SLC6A20 SMARCE1 SMCP SPACA9 SPATA3 SPATA8 SPG7 SPRY1 SPRY2 STK16 TBC1D16 TBC1D23 TBC1D26 TEDC2 TGOLN2 THAP10 TLE5 TNFRSF6B TNP2 TRIM41 TRIM42 TXNDC5 TYMSOS TYRO3 UTP23 VGLL3 WNT11 WT1 WT1-AS XCL2 YIPF3 YY1 ZBTB24 ZBTB38 ZBTB9 ZFYVE26 ZNF124 ZNF155 ZNF165 ZNF20 ZNF251 ZNF264 ZNF275 ZNF286A ZNF317 ZNF319 ZNF417 ZNF433 ZNF439 ZNF440 ZNF473 ZNF497 ZNF524 ZNF564 ZNF572 ZNF578 ZNF581 ZNF587 ZNF599 ZNF625 ZNF688 ZNF696 ZNF697 ZNF699 ZNF764 ZNF774 ZNF777 ZNF792 ZNF80 ZNF837 ZNF844 ZNF860 ZSCAN21 ZSCAN26	69 interacting genes: ADAMTSL4 AGTRAP AJUBA AP1B1 APPL1 BACH2 BAG4 BANP BEX5 CALCOCO2 CBY2 CCDC152 CDCA4 CMTM5 CYSRT1 DGAT2L6 DPH2 DVL3 FHL5 FKBP7 FSD2 GRB10 HIGD1C HMBOX1 HOMEZ IKZF3 ISY1-RAB43 KCNF1 KCTD17 KRT13 KRT31 KRT34 KRT40 KRTAP1-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP3-3 MAN1C1 MDFI MESD MID2 MKRN3 MORN3 NFKBID NOTCH2NLA PCSK5 PPP1R16B RCBTB2 RIMBP3C SPRY1 STX11 SYP TADA2A TEPSIN TFCP2 TPM2 TRAF2 TRIM27 TRIM54 TRIP6 YIF1A ZNF438 ZNF500 ZNF526 ZNF655 ZRANB1
Entrez ID		386676	10667
HPRD ID		11195	09946
Ensembl ID		ENSG00000221837	ENSG00000145982
Uniprot IDs		P60411	O95363
PDB IDs			3CMQ 3HFV 3TEG 3TUP 5MGH 5MGU 5MGV 5MGW
Enriched GO Terms of Interacting Partners?
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