KRT14 and KRT78

Data Source:
BioGRID (two hybrid)

		KRT14	KRT78
Description		keratin 14	keratin 78
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Intermediate Filament Keratin Filament Basal Part Of Cell Extracellular Exosome Cell Periphery	Extracellular Space Cytosol Keratin Filament Extracellular Exosome
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Keratin Filament Binding	Protein Binding
	Biological Process	Aging Epidermis Development Response To Zinc Ion Response To Ionizing Radiation Keratinization Hemidesmosome Assembly Hair Cycle Intermediate Filament Bundle Assembly Cornification	Keratinization Cornification
Pathways		Type I hemidesmosome assembly Keratinization Formation of the cornified envelope	Keratinization Formation of the cornified envelope
Drugs		Zinc Zinc acetate
Diseases		Naegeli-Franceschetti-Jadassohn syndrome Dermatopathia pigmentosa reticularis Epidermolysis bullosa simplex, including: Epidermolysis bullosa simplex, Dowling-Meara type (EBS-DM); Epidermolysis bullosa simplex, Koebner type (EBS-K); Epidermolysis bullosa simplex, Weber-Cockayne type (EBS-WC); Epidermolysis bullosa simplex with mottled pigmentation (EBS-MP); Epidermolysis bullosa simplex with migratory circinate erythema; Epidermolysis bullosa simplex, recessive; Epidermolysis bullosa, lethal acantholytic
GWAS			Gamma glutamyl transferase levels ( 29403010)
Interacting Genes		32 interacting genes: ABI2 ABI3 AMOT APC BFSP2 CTTNBP2 DST ENKD1 GAS8 HGS HSPA5 KIFC3 KRT1 KRT3 KRT5 KRT6C KRT72 KRT78 KRT79 KRT80 KRT81 KRT86 OIP5 PKP1 PRPH PUS10 SDCBP SMARCE1 TCHP TRADD UBASH3A USHBP1	16 interacting genes: C14orf119 KRT14 KRT15 KRT16 KRT19 KRT25 KRT27 KRT31 KRT33B KRT34 KRT35 KRT36 KRT39 SRPK2 TRIM54 UCHL5
Entrez ID		3861	196374
HPRD ID		01017	17171
Ensembl ID		ENSG00000186847	ENSG00000170423
Uniprot IDs		P02533	Q8N1N4
PDB IDs		3TNU 6JFV
Enriched GO Terms of Interacting Partners?
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