KRT10 and EVPL

Data Source:
HPRD (in vivo)

		KRT10	EVPL
Description		keratin 10	envoplakin
Image
GO Annotations	Cellular Component	Cornified Envelope Extracellular Space Nucleus Cytoplasm Cytosol Intermediate Filament Cell Surface Membrane Extracellular Exosome	Cornified Envelope Cytoplasm Cytosol Intermediate Filament Membrane Desmosome Intermediate Filament Cytoskeleton Extracellular Exosome
	Molecular Function	Protein Binding Structural Constituent Of Skin Epidermis Protein Heterodimerization Activity	Structural Molecule Activity Intermediate Filament Binding Cadherin Binding
	Biological Process	Peptide Cross-linking Keratinocyte Differentiation Keratinization Positive Regulation Of Epidermis Development Protein Heterotetramerization Cornification	Epidermis Development Peptide Cross-linking Keratinocyte Differentiation Wound Healing Intermediate Filament Cytoskeleton Organization Cornification
Pathways		Keratinization Formation of the cornified envelope	Formation of the cornified envelope
Drugs		Zinc Copper Zinc acetate
Diseases		Ichthyosis with confetti; Congenital reticular ichthyosiform erythroderma; Ichthyosis variegata Epidermolytic hyperkeratosis (EHK); Bullous congenital ichthyosiform erythroderma (BCIE)
GWAS		Glucose homeostasis traits ( 25524916)	Deep white matter hyperintensities ( 32517579) Depressive symptom improvement ( 30468137) L-selectin levels ( 25576479) Metabolite levels ( 23823483) Periventricular white matter hyperintensities ( 32517579)
Interacting Genes		8 interacting genes: AKT1 ESR1 EVPL GLE1 PRKCZ SIRPA SMAD3 SNAPIN	14 interacting genes: CSTA DSP IVL KRT1 KRT10 KRT2 KRT5 LORICRIN PI3 PLEKHA5 PPL PSORS1C2 SPRR2A SPRR3
Entrez ID		3858	2125
HPRD ID		01021	03352
Ensembl ID		ENSG00000186395	ENSG00000167880
Uniprot IDs		P13645	B7ZLH8 K7EKI0 Q92817
PDB IDs		3ASW 4F1Z 4ZRY 6E2J 6EC0 6UUI	4QMD
Enriched GO Terms of Interacting Partners?
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