KRT6A and GNL1

Data Source:
BioGRID (affinity chromatography technology)

		KRT6A	GNL1
Description		keratin 6A	G protein nucleolar 1 (putative)
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Membrane Keratin Filament Extracellular Exosome	Extracellular Space Nucleus
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding	GTPase Activity Structural Molecule Activity GTP Binding
	Biological Process	Negative Regulation Of Cytolysis By Symbiont Of Host Cells Morphogenesis Of An Epithelium Cytoskeleton Organization Positive Regulation Of Cell Population Proliferation Cell Differentiation Keratinization Wound Healing Defense Response To Gram-positive Bacterium Cytolysis By Host Of Symbiont Cells Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Cornification Negative Regulation Of Entry Of Bacterium Into Host Cell	T Cell Mediated Immunity Cellular Response To DNA Damage Stimulus Signal Transduction
Pathways		Keratinization Formation of the cornified envelope
Drugs		Zinc Zinc acetate
Diseases		Pachyonychia congenita, including: Jadassohn-Lewandowsky syndrome; Jackson-Lawler syndrome ; Steatocystoma multiplex
GWAS		Cutaneous squamous cell carcinoma ( 32041948)	Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Lung cancer ( 28604730) Major depressive disorder ( 27479909) Neuroticism ( 29255261) Rosacea symptom severity ( 29771307) Squamous cell lung carcinoma ( 28604730)
Interacting Genes		38 interacting genes: BEX2 CCDC85B DSP GEM GOLGA2 HGS KDM1A KIFC3 KRT13 KRT15 KRT16 KRT17 KRT18 KRT19 KRT25 KRT26 KRT27 KRT28 KRT31 KRT34 KRT35 KRT36 KRT38 KRT40 LMNA MTUS2 NCALD NUP62 SGTA SMARCB1 TCHP TFIP11 TRIM23 TRIM54 TSGA10 TXLNB UBQLN2 WASHC3	4 interacting genes: GDI1 PTP4A1 SIRPA ZNF212
Entrez ID		3853	2794
HPRD ID		01011	00879
Ensembl ID		ENSG00000205420	ENSG00000204590
Uniprot IDs		A0A0S2Z428 P02538	A0A024RCR2 B4DYK6 P36915
PDB IDs		5KI0
Enriched GO Terms of Interacting Partners?
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