KLK1 and SERPINA4

		KLK1	SERPINA4
Description		kallikrein 1	serpin family A member 4
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GO Annotations	Cellular Component	Nucleus Secretory Granule Extracellular Exosome	Extracellular Region Extracellular Space Platelet Dense Granule Lumen Extracellular Exosome
	Molecular Function	Serine-type Endopeptidase Activity	Serine-type Endopeptidase Inhibitor Activity
	Biological Process	Regulation Of Systemic Arterial Blood Pressure Zymogen Activation	Platelet Degranulation Negative Regulation Of Endopeptidase Activity
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)	Platelet degranulation
Drugs		Aluminium Benzamidine Lanoteplase Aprotinin Aniline Nafamostat Aluminium phosphate Aluminum acetate	Zinc Copper Zinc acetate
Diseases
GWAS		Dental caries (decayed, missing and filled tooth surfaces) ( 31533690)	Blood protein levels ( 30072576 29875488 28240269) Vaspin levels ( 22907691)
Interacting Genes		8 interacting genes: A2M ITIH4 KNG1 PROC SERPINA1 SERPINA4 SERPINA5 SERPINC1	13 interacting genes: CTSD GADD45G ILK KLK1 KLK2 MAP4K2 MAPK6 NR4A1 RASA1 TAB1 TNFRSF14 TNNT1 YAE1
Entrez ID		3816	5267
HPRD ID		01003	01004
Ensembl ID		ENSG00000167748	ENSG00000100665
Uniprot IDs		A0A1L2BPJ2 A0A1R3UCD2 P06870	A0A024R6I9 P29622
PDB IDs		1SPJ	6F02
Enriched GO Terms of Interacting Partners?
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