KEL and EMC1

Data Source:
BioGRID (proximity labelling technology)

		KEL	EMC1
Description		Kell metallo-endopeptidase (Kell blood group)	ER membrane protein complex subunit 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Plasma Membrane Integral Component Of Membrane	Endoplasmic Reticulum Membrane Integral Component Of Membrane Integral Component Of Endoplasmic Reticulum Membrane Protein-containing Complex EMC Complex
	Molecular Function	Metalloendopeptidase Activity Protein Binding Metal Ion Binding	Membrane Insertase Activity
	Biological Process	Cellular Calcium Ion Homeostasis Regulation Of Cell Size Cellular Magnesium Ion Homeostasis Protein Processing Regulation Of Axon Diameter Vasoconstriction Myelination Skeletal Muscle Fiber Development Negative Regulation Of Potassium Ion Transmembrane Transport	Protein Insertion Into ER Membrane By Stop-transfer Membrane-anchor Sequence Tail-anchored Membrane Protein Insertion Into ER Membrane
Pathways		Peptide ligand-binding receptors
Drugs		Phosphoramidon
Diseases
GWAS		Alcoholic chronic pancreatitis ( 28754779) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494 27863252)
Interacting Genes		12 interacting genes: ADIPOQ C3orf52 C5 CLDN19 EDN1 EDN2 EDN3 EWSR1 PM20D2 TUBA1A UBC XK
Entrez ID		3792	23065
HPRD ID		00194	08306
Ensembl ID		ENSG00000197993	ENSG00000127463
Uniprot IDs		A0A077QP03 P23276	Q8N766
PDB IDs			6WW7 6Z3W
Enriched GO Terms of Interacting Partners?
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