KCNN3 and SLC27A3

Data Source:
BioGRID (proximity labelling technology)

		KCNN3	SLC27A3
Description		potassium calcium-activated channel subfamily N member 3	solute carrier family 27 member 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Neuron Projection Neuronal Cell Body	Mitochondrion Endoplasmic Reticulum Membrane Integral Component Of Membrane Mitochondrial Membrane
	Molecular Function	Calmodulin Binding Small Conductance Calcium-activated Potassium Channel Activity	Long-chain Fatty Acid-CoA Ligase Activity Long-chain Fatty Acid Transporter Activity ATP Binding Very Long-chain Fatty Acid-CoA Ligase Activity Arachidonate-CoA Ligase Activity
	Biological Process	Ion Transport Potassium Ion Transmembrane Transport	Long-chain Fatty Acid Metabolic Process Fatty Acid Transport Long-chain Fatty Acid Transport
Pathways		Ca2+ activated K+ channels	Synthesis of very long-chain fatty acyl-CoAs
Drugs		Procaine Miconazole Trimebutine
Diseases
GWAS		Alzheimer's disease in APOE e4- carriers ( 25778476) Atrial fibrillation ( 28416818 29290336 30061737 29892015 20173747 22544366) Bipolar disorder ( 31043756) Birth weight ( 31043758) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Height ( 28552196) Incident atrial fibrillation ( 28416818) Obesity-related traits ( 23251661) Offspring birth weight ( 31043758) Prevalent atrial fibrillation ( 28416818) Prostate cancer ( 23535732) Squamous cell lung carcinoma ( 28604730) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Waist circumference adjusted for body mass index ( 28552196)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Chronotype ( 30696823) Cooked vegetable consumption ( 32066663) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Fish- and plant-related diet ( 32066663) Fruit consumption ( 32066663) Height ( 31562340) Number of children ever born ( 27798627) Raw vegetable consumption ( 32066663) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		7 interacting genes: APP CALM1 CLCN7 EMD ERMP1 FCER1G NAPB
Entrez ID		3782	11000
HPRD ID		04283	11967
Ensembl ID		ENSG00000143603	ENSG00000143554
Uniprot IDs		A0A087WYJ0 Q9UGI6	Q5K4L6 X6R3N0
PDB IDs
Enriched GO Terms of Interacting Partners?
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