KCNN2 and DCP2

Data Source:
BioGRID (proximity labelling technology)

		KCNN2	DCP2
Description		potassium calcium-activated channel subfamily N member 2	decapping mRNA 2
Image
GO Annotations	Cellular Component	Plasma Membrane Cell Surface Integral Component Of Membrane Z Disc Neuron Projection Neuronal Cell Body Dendritic Spine	P-body Nucleoplasm Cytoplasm Cytosol RISC Complex Cell Junction Cytoplasmic Ribonucleoprotein Granule
	Molecular Function	Protein Binding Calmodulin Binding Calcium-activated Potassium Channel Activity Small Conductance Calcium-activated Potassium Channel Activity Protein Domain Specific Binding Protein Homodimerization Activity Alpha-actinin Binding	5'-3' Exoribonuclease Activity Protein Binding Exoribonuclease Activity, Producing 5'-phosphomonoesters Manganese Ion Binding M7G(5')pppN Diphosphatase Activity Telomerase RNA Binding
	Biological Process	Ion Transport Potassium Ion Transport Potassium Ion Transmembrane Transport Membrane Repolarization During Atrial Cardiac Muscle Cell Action Potential Regulation Of Potassium Ion Transmembrane Transport	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA MRNA Catabolic Process Negative Regulation Of Telomere Maintenance Via Telomerase Regulation Of MRNA Stability Exonucleolytic Catabolism Of Deadenylated MRNA Histone MRNA Catabolic Process RNA Phosphodiester Bond Hydrolysis, Exonucleolytic Regulation Of Telomerase RNA Localization To Cajal Body
Pathways		Ca2+ activated K+ channels	ATF4 activates genes in response to endoplasmic reticulum stress mRNA decay by 5' to 3' exoribonuclease Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA KSRP (KHSRP) binds and destabilizes mRNA
Drugs		Procaine Miconazole Trimebutine
Diseases
GWAS		Alzheimer disease and age of onset ( 26830138) Atrial fibrillation ( 28416818 30061737 29892015) Coronary arterial lesions in patients with Kawasaki disease ( 23677057) Diastolic blood pressure ( 27841878) Generalized epilepsy ( 30531953) JT interval (sulfonylurea treatment interaction) ( 27958378) Night sleep phenotypes ( 27126917) Obesity-related traits ( 23251661) Systolic blood pressure ( 27841878)	Worry/vulnerability (special factor of neuroticism) ( 30867560)
Interacting Genes		4 interacting genes: ACTN2 CALM1 SRPK1 SRPK2	12 interacting genes: AGO1 AGO2 DCP1A DCP1B MIR15B MTOR NAGK POLA2 PSMB1 TRIM21 UPF1 UPF2
Entrez ID		3781	167227
HPRD ID		09323	13125
Ensembl ID		ENSG00000080709	ENSG00000172795
Uniprot IDs		A0A3F2YNY5 Q9H2S1	Q8IU60
PDB IDs		5V02 5WBX 5WC5 6ALE	5MP0 5QOH 5QOI 5QOJ 5QOK 5QOL 5QOM 5QON 5QOO 5QOP 5QOQ 5QOR 5QOS 5QOT 5QOU 5QOV 5QOW 5QOX 5QOY 5QOZ 5QP0 5QP1 5QP2 5QP3 5QP4 5QP5 5QP6 5QP7 5QP8 5QP9 5QPA 5QPB 5QPC
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?