CA13 and CRTC3

Data Source:
BioGRID (two hybrid)

		CA13	CRTC3
Description		carbonic anhydrase 13	CREB regulated transcription coactivator 3
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Myelin Sheath Intracellular Membrane-bounded Organelle	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Carbonate Dehydratase Activity Protein Binding Zinc Ion Binding Hydro-lyase Activity	Protein Binding CAMP Response Element Binding Protein Binding
	Biological Process	One-carbon Metabolic Process Bicarbonate Transport	Viral Process Positive Regulation Of CREB Transcription Factor Activity Macrophage Activation Negative Regulation Of CAMP-mediated Signaling Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Lipid Catabolic Process Protein Homotetramerization Energy Homeostasis
Pathways		Reversible hydration of carbon dioxide	Transcriptional activation of mitochondrial biogenesis Circadian Clock
Drugs		Benzthiazide Cyclothiazide Zonisamide N-(4-chlorobenzyl)-N-methylbenzene-1,4-disulfonamide
Diseases
GWAS		Blood protein levels ( 30072576 28240269) Blood trace element (Zn levels) ( 23720494)	Apolipoprotein B levels ( 32203549) Chromium levels ( 26025379) Chronic postoperative pain ( 31903573) Colorectal cancer ( 29228715) Daytime sleep phenotypes ( 27126917) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Gastroesophageal reflux disease ( 27485664) Heel bone mineral density ( 28869591) Inflammatory bowel disease ( 28067908 23128233) Information processing speed ( 21130836) Male-pattern baldness ( 28196072) Offspring birth weight ( 31043758) Response to exercise (triglyceride level interaction) ( 26491034) Ulcerative colitis ( 28067908)
Interacting Genes		2 interacting genes: CRACR2B CRTC3	4 interacting genes: CA13 KLHL12 SIK2 YWHAG
Entrez ID		377677	64784
HPRD ID		12992	13384
Ensembl ID		ENSG00000185015	ENSG00000140577
Uniprot IDs		Q8N1Q1	Q6UUV7 Q8TEF4
PDB IDs		3CZV 3D0N 3DA2 4HU1 4KNM 4KNN 4QIZ 4QJP 4QJX 4QSJ 5E2N 5LLA 5LLN 5OGJ 5OHH 6G5U
Enriched GO Terms of Interacting Partners?
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