KCNJ16 and KCNJ15

Data Source:
HPRD (in vivo, in vitro)

		KCNJ16	KCNJ15
Description		potassium inwardly rectifying channel subfamily J member 16	potassium inwardly rectifying channel subfamily J member 15
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Voltage-gated Potassium Channel Complex Basolateral Plasma Membrane	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Inward Rectifier Potassium Channel Activity	Inward Rectifier Potassium Channel Activity Protein Binding
	Biological Process	Potassium Ion Transport Regulation Of Ion Transmembrane Transport Potassium Ion Import Across Plasma Membrane	Potassium Ion Transport Regulation Of Ion Transmembrane Transport Potassium Ion Import Across Plasma Membrane
Pathways		Activation of G protein gated Potassium channels Potassium transport channels Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits	Activation of G protein gated Potassium channels Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
Drugs			Yohimbine Butamben
Diseases
GWAS		Birth weight ( 31043758) Body mass index ( 26426971) Cerebral amyloid deposition in APOEe4 non-carriers (PET imaging) ( 26252872) Metabolite levels ( 23823483) Palmitoleic acid (16:1n-7) levels ( 23362303) Periodontitis (DPAL) ( 24024966) Primary tooth development (number of teeth) ( 23704328) Primary tooth development (time to first tooth eruption) ( 23704328) Serum metabolite levels ( 25569235) Thyrotoxic hypokalemic periodic paralysis ( 22863731) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Basophil count ( 32888494) Basophil percentage of white cells ( 32888494) Height ( 31562340) Metabolite levels ( 23823483) Non-response to antidepressants and depression ( 27622933)
Interacting Genes		4 interacting genes: KCNJ10 KCNJ15 KCNJ2 NEDD4	6 interacting genes: IL16 KCNJ16 KCNJ2 KCNJ5 PATJ SNTA1
Entrez ID		3773	3772
HPRD ID		16146	03659
Ensembl ID		ENSG00000153822	ENSG00000157551
Uniprot IDs		A8K434 K7EJR9 Q8N538 Q9NPI9	Q99712
PDB IDs
Enriched GO Terms of Interacting Partners?
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