KCNJ12 and ABLIM1

Data Source:
HPRD (in vitro)

		KCNJ12	ABLIM1
Description		potassium inwardly rectifying channel subfamily J member 12	actin binding LIM protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Intrinsic Component Of Membrane	Stress Fiber Cytoplasm Actin Cytoskeleton Lamellipodium
	Molecular Function	Inward Rectifier Potassium Channel Activity Protein Binding	Actin Binding Protein Binding Metal Ion Binding Actin Filament Binding
	Biological Process	Potassium Ion Transport Muscle Contraction Regulation Of Heart Contraction Regulation Of Ion Transmembrane Transport Protein Homotetramerization Cardiac Conduction Potassium Ion Import Across Plasma Membrane	Cytoskeleton Organization Visual Perception Animal Organ Morphogenesis Lamellipodium Assembly Cilium Assembly
Pathways		Activation of G protein gated Potassium channels Classical Kir channels Phase 4 - resting membrane potential Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits	DCC mediated attractive signaling
Drugs		Dofetilide Ranolazine Miconazole Yohimbine Dronedarone Butamben
Diseases
GWAS		Adult body size ( 32376654) Body mass index ( 28892062 25673413) Height ( 20881960 31562340) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Red blood cell count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Waist-hip ratio ( 25673412)	Age-related cognitive decline (memory) (slope of z-scores) ( 30954325) Metabolite levels ( 23823483) Obesity-related traits ( 23251661) Paclitaxel disposition in epithelial ovarian cancer ( 29367611) Taste perception (total score including 6-n-propylthiouracil) in obesity with metabolic syndrome ( 31005965)
Interacting Genes		17 interacting genes: ABLIM1 APBA1 CASK DLG1 DLG2 DLG3 DLG4 DMD DTNA EMD LIN7A LIN7B LIN7C PRKACA SNTA1 SNTB1 SNTB2	25 interacting genes: ACTB ACTG1 APP BEGAIN CALCOCO2 CARD9 CCDC57 DAPK1 FHL2 GOLGA2 HOOK2 HSF2BP KCNJ12 KRT15 LDOC1 LRRK2 MFHAS1 PTPRD SREBF2 TRAF2 TSC22D4 TTN USHBP1 VIM YWHAG
Entrez ID		3768	3983
HPRD ID		09083	03819
Ensembl ID		ENSG00000184185	ENSG00000099204
Uniprot IDs		Q14500	B3KSG3 B4DQA3 O14639
PDB IDs
Enriched GO Terms of Interacting Partners?
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