KCNA10 and DOLK

Data Source:
BioGRID (two hybrid)

		KCNA10	DOLK
Description		potassium voltage-gated channel subfamily A member 10	dolichol kinase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Voltage-gated Potassium Channel Complex Integral Component Of Membrane	Endoplasmic Reticulum Membrane Integral Component Of Endoplasmic Reticulum Membrane
	Molecular Function	Intracellular Cyclic Nucleotide Activated Cation Channel Activity Voltage-gated Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Protein Binding	Dolichol Kinase Activity Protein Binding
	Biological Process	Potassium Ion Transport Regulation Of Ion Transmembrane Transport Protein Homooligomerization Potassium Ion Transmembrane Transport	Dolichyl Diphosphate Biosynthetic Process Phosphorylation Dolichyl Monophosphate Biosynthetic Process
Pathways		Voltage gated Potassium channels	Synthesis of Dolichyl-phosphate Defective DOLK causes DOLK-CDG (CDG-1m)
Drugs		Enflurane Promethazine Miconazole Dalfampridine
Diseases			Congenital disorders of glycosylation (CDG) type I
GWAS		Bitter taste perception (phenylthiocarbamide) in obesity with metabolic syndrome ( 31005965) Response to bupropion in depression ( 27622933)
Interacting Genes		6 interacting genes: DOLK KCNA1 MAL POMP SGTA TMBIM6	22 interacting genes: APPBP2 CD79A CHODL CREB3 CREB3L1 EDA FAM209A FNDC9 GALNT8 GJA8 GPX8 KCNA1 KCNA10 KCNA3 KCNA6 LRRC4C SLC7A6 SYNPR TMEM45B TMEM80 UBQLN1 VSIR
Entrez ID		3744	22845
HPRD ID		03882	15525
Ensembl ID		ENSG00000143105	ENSG00000175283
Uniprot IDs		Q16322	A0A0S2Z597 Q9UPQ8
PDB IDs
Enriched GO Terms of Interacting Partners?
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