CCDC172 and ISCU

		CCDC172	ISCU
Description		coiled-coil domain containing 172	iron-sulfur cluster assembly enzyme
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Sperm Midpiece	Nucleus Cytoplasm Mitochondrion Mitochondrial Matrix Cytosol
	Molecular Function	Protein Binding	Iron Ion Binding Protein Binding Ferrous Iron Binding 2 Iron, 2 Sulfur Cluster Binding 4 Iron, 4 Sulfur Cluster Binding Molecular Adaptor Activity
	Biological Process		Cellular Iron Ion Homeostasis Iron-sulfur Cluster Assembly Small Molecule Metabolic Process Positive Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Positive Regulation Of Aconitate Hydratase Activity Negative Regulation Of Iron Ion Import Across Plasma Membrane
Pathways
Drugs
Diseases
GWAS		Epilepsy and lamotrigine-induced maculopapular eruptions ( 26220383) Malaria ( 31844061)	Acne (severe) ( 24927181) Intraocular pressure ( 29617998)
Interacting Genes		21 interacting genes: C2CD6 DCTN2 FAM13C FAM161B HDDC3 ISCU KDM1A MRPL11 MSGN1 NEFL PCDHB12 PCM1 PLEKHF2 PRKAA2 PSTPIP1 SH2D4A SMARCE1 TCHP TEAD4 TXNDC9 VPS9D1	17 interacting genes: AGTRAP BANP CBY2 CCDC136 CCDC172 FAM9B GOLGA2 GOLGA6L9 HPRT1 IKZF1 KRT34 KRT40 LNX1 MID2 NECAB2 NUP62 PICK1
Entrez ID		374355	23479
HPRD ID		18604	14828
Ensembl ID		ENSG00000182645	ENSG00000136003
Uniprot IDs		P0C7W6	A0A024RBI3 B1P7G3 B3KQ30 B4DNC9 Q9H1K1
PDB IDs			5KZ5 5WKP 5WLW 6NZU 6UXE 6W1D 6WI2 6WIH
Enriched GO Terms of Interacting Partners?
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