ITPKB and SCAI

Data Source:
BioGRID (two hybrid)

		ITPKB	SCAI
Description		inositol-trisphosphate 3-kinase B	suppressor of cancer cell invasion
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Membrane	Nucleus Nucleoplasm Cytoplasm Integral Component Of Membrane Nuclear Membrane
	Molecular Function	Inositol Hexakisphosphate Kinase Activity Protein Binding Calmodulin Binding ATP Binding Inositol-1,4,5-trisphosphate 3-kinase Activity Kinase Activity	Transcription Corepressor Activity Protein Binding
	Biological Process	MAPK Cascade Regulation Of Protein Phosphorylation Myeloid Cell Homeostasis Signal Transduction Cell Surface Receptor Signaling Pathway Inositol Trisphosphate Metabolic Process Inositol Phosphate Biosynthetic Process Negative Regulation Of Neutrophil Apoptotic Process Common Myeloid Progenitor Cell Proliferation Inositol Phosphate Metabolic Process Positive Thymic T Cell Selection Negative Regulation Of Myeloid Cell Differentiation Positive Regulation Of Ras Protein Signal Transduction Positive Regulation Of Alpha-beta T Cell Differentiation Phosphatidylinositol Phosphorylation Cellular Response To Calcium Ion	Transcription, DNA-templated Negative Regulation Of Cell Migration Negative Regulation Of Rho Protein Signal Transduction Negative Regulation Of Transcription, DNA-templated
Pathways		Synthesis of IP3 and IP4 in the cytosol	RHO GTPases Activate Formins
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406) Asthma ( 32296059) Dentures ( 31235808) Eosinophil percentage of white cells ( 32888494) Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808) Parkinson's disease ( 32201043 28892059 32310270) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Refractive error ( 32231278) Subcutaneous adipose tissue ( 22589738)	Pulse pressure ( 28135244 30578418) Refractive error ( 32231278) Worry too long after an embarrassing experience ( 29500382)
Interacting Genes		13 interacting genes: CALM1 CEP70 CTDSP1 GOLGA2 IFT88 KRT34 PPP3CA PRKACA PRKCA PSME3 SCAI TRIM54 UBQLN2	5 interacting genes: CDIPT ITPKB OGT PIN1 SOX7
Entrez ID		3707	286205
HPRD ID		00942	12941
Ensembl ID		ENSG00000143772	ENSG00000173611
Uniprot IDs		B2R9J0 P27987	Q8N9R8
PDB IDs
Enriched GO Terms of Interacting Partners?
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