ACADVL and GPHN

Data Source:
BioGRID (two hybrid)

		ACADVL	GPHN
Description		acyl-CoA dehydrogenase very long chain	gephyrin
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GO Annotations	Cellular Component	Nucleoplasm Nucleolus Mitochondrion Mitochondrial Matrix Extrinsic Component Of Mitochondrial Inner Membrane Mitochondrial Membrane Mitochondrial Nucleoid	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Postsynaptic Density Dendrite Postsynaptic Membrane Synaptic Membrane Anchored Component Of Synaptic Membrane Postsynaptic Specialization Postsynaptic Specialization Membrane
	Molecular Function	Fatty-acyl-CoA Binding Acyl-CoA Dehydrogenase Activity Long-chain-acyl-CoA Dehydrogenase Activity Protein Binding Very-long-chain-acyl-CoA Dehydrogenase Activity Identical Protein Binding Flavin Adenine Dinucleotide Binding	Protein Binding ATP Binding Nitrate Reductase Activity Identical Protein Binding Molybdopterin Cofactor Binding Metal Ion Binding Molybdopterin Adenylyltransferase Activity Molybdopterin Molybdotransferase Activity
	Biological Process	Temperature Homeostasis Fatty Acid Beta-oxidation Response To Cold Energy Derivation By Oxidation Of Organic Compounds Epithelial Cell Differentiation Fatty Acid Beta-oxidation Using Acyl-CoA Dehydrogenase IRE1-mediated Unfolded Protein Response Negative Regulation Of Fatty Acid Biosynthetic Process Negative Regulation Of Fatty Acid Oxidation Regulation Of Cholesterol Metabolic Process	Mo-molybdopterin Cofactor Biosynthetic Process Establishment Of Synaptic Specificity At Neuromuscular Junction Response To Metal Ion Molybdenum Incorporation Into Molybdenum-molybdopterin Complex Molybdopterin Cofactor Biosynthetic Process Glycine Receptor Clustering Gamma-aminobutyric Acid Receptor Clustering Postsynaptic Neurotransmitter Receptor Diffusion Trapping
Pathways		XBP1(S) activates chaperone genes Beta oxidation of palmitoyl-CoA to myristoyl-CoA	Molybdenum cofactor biosynthesis
Drugs			Formic acid Imidazole Propanoic acid
Diseases		Disorders of fatty-acid oxidation, including: Medium-chain (MC) acyl-CoA dehydrogenase (AD) deficiency (MCADD); Short-chain AD deficiency (SCADD) ; Short-branched-chain AD deficiency (SBCADD) ; Very long-chain AD deficiency (VLCADD) ; Long-chain 3-hydroxyacyl CoA dehydrogenase deficiency (LCHADD) ; Trifunctional protein deficiency (TFP); Carnitine palmitoyltransferase deficiency (CPT); Carnitine-acylcarnitine translocase deficiency (CACT); Systemic primary carnitine deficiency (CDSP)	Hyperekplexia
GWAS		Metabolite levels ( 23823483)	Depression (quantitative trait) ( 23290196) Pneumococcal meningitis ( 31092817) Tandem gait ( 26219847) Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		5 interacting genes: GPHN LINC01554 RPSA SOCS3 TAF1B	15 interacting genes: ACADVL ARHGEF9 DYNLL1 DYNLL2 ENAH GABARAP GLRB KHDRBS1 MITD1 MTOR PFN1 PIN1 PSMA1 SPATS1 TUBA4A
Entrez ID		37	10243
HPRD ID		01940	04893
Ensembl ID		ENSG00000072778	ENSG00000171723
Uniprot IDs		B3KPA6 P49748	Q9NQX3
PDB IDs		2UXW 3B96	1JLJ
Enriched GO Terms of Interacting Partners?
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