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IL17A and KCNIP4
Data Source:
BioGRID
(two hybrid)
IL17A
KCNIP4
Description
interleukin 17A
potassium voltage-gated channel interacting protein 4
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
External Side Of Plasma Membrane
Cytoplasm
Endoplasmic Reticulum
Cytosol
Plasma Membrane
Voltage-gated Potassium Channel Complex
Molecular Function
Cytokine Activity
Protein Binding
Protein Homodimerization Activity
Protein Heterodimerization Activity
Voltage-gated Ion Channel Activity
Potassium Channel Activity
Calcium Ion Binding
Protein Binding
Potassium Channel Regulator Activity
Biological Process
Positive Regulation Of Antimicrobial Peptide Production
Adaptive Immune Response
Apoptotic Process
Inflammatory Response
Immune Response
Cell-cell Signaling
Cell Death
Cytokine-mediated Signaling Pathway
Positive Regulation Of Interleukin-1 Beta Production
Positive Regulation Of Interleukin-12 Production
Positive Regulation Of Interleukin-16 Production
Positive Regulation Of Interleukin-23 Production
Positive Regulation Of Interleukin-6 Production
Positive Regulation Of Tumor Necrosis Factor Production
Innate Immune Response
Positive Regulation Of Osteoclast Differentiation
Positive Regulation Of Transcription By RNA Polymerase II
Defense Response To Gram-negative Bacterium
Defense Response To Gram-positive Bacterium
Defense Response To Fungus
Intestinal Epithelial Structure Maintenance
Cellular Response To Interleukin-1
Fibroblast Activation
Interleukin-17-mediated Signaling Pathway
Granulocyte Migration
Positive Regulation Of Cytokine Production Involved In Inflammatory Response
Positive Regulation Of Bicellular Tight Junction Assembly
Positive Regulation Of Chemokine (C-X-C Motif) Ligand 1 Production
Cardiac Conduction
Potassium Ion Transmembrane Transport
Protein Localization To Plasma Membrane
Regulation Of Potassium Ion Transmembrane Transport
Pathways
Interleukin-17 signaling
Interleukin-4 and Interleukin-13 signaling
Phase 1 - inactivation of fast Na+ channels
Drugs
Secukinumab
Ixekizumab
Diseases
GWAS
Height (
28552196
)
Cadmium levels (
26025379
)
Colorectal cancer (
29228715
)
Cough in response to angiotensin-converting enzyme inhibitor drugs (
26169577
)
Diverticular disease (
30177863
)
Lingual gyrus volume (
31530798
)
Obesity-related traits (
23251661
)
Parkinson disease and lewy body pathology (
25663231
)
Post bronchodilator FEV1/FVC ratio (
26634245
)
Postburn scar height (
30595539
)
Rheumatoid arthritis (
21156761
)
Suicidal ideation (
20877300
)
Interacting Genes
3 interacting genes:
DPH2
IL17RA
KCNIP4
11 interacting genes:
APP
ASPH
COL1A2
GOLGA7
IL17A
KCND2
LITAF
MEOX2
PSEN1
PSEN2
TRH
Entrez ID
3605
80333
HPRD ID
04396
12184
Ensembl ID
ENSG00000112115
ENSG00000185774
Uniprot IDs
Q16552
A8K4N3
Q6PIL6
PDB IDs
2VXS
4HR9
4HSA
4QHU
5HHV
5HHX
5HI3
5HI4
5HI5
5N7W
5N92
5NAN
5VB9
6WIO
6WIR
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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