TNFRSF9 and AP1S1

Data Source:
BioGRID (genetic interference)

		TNFRSF9	AP1S1
Description		TNF receptor superfamily member 9	adaptor related protein complex 1 subunit sigma 1
Image
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane	Golgi Membrane Lysosomal Membrane Golgi Apparatus Cytosol Clathrin-coated Pit Membrane AP-1 Adaptor Complex Cytoplasmic Vesicle Membrane Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Cytokine Binding Signaling Receptor Activity
	Biological Process	Apoptotic Process Negative Regulation Of Cell Population Proliferation Tumor Necrosis Factor-mediated Signaling Pathway Regulation Of Cell Population Proliferation	Intracellular Protein Transport Receptor-mediated Endocytosis Response To Virus Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Regulation Of Defense Response To Virus By Virus
Pathways		TNFs bind their physiological receptors	Nef mediated downregulation of MHC class I complex cell surface expression MHC class II antigen presentation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis
Drugs		Urelumab
Diseases
GWAS		Blond vs. brown/black hair color ( 30531825) Celiac disease ( 20190752) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908 23128233) Psoriasis ( 25903422 23143594) Rheumatoid arthritis ( 30423114 24390342) Ulcerative colitis ( 28067908 21297633) Waist-hip ratio ( 28552196)	Adult body size ( 32376654)
Interacting Genes		7 interacting genes: LRR1 SERP1 TNFRSF4 TNFSF9 TRAF1 TRAF2 TRAF3	6 interacting genes: AP1G1 AP1G2 AP1M2 AP2A2 PICK1 RHOU
Entrez ID		3604	1174
HPRD ID		03767	04635
Ensembl ID		ENSG00000049249	ENSG00000106367
Uniprot IDs		Q07011	A0A024QYT6 P61966
PDB IDs		6A3V 6A3W 6BWV 6CPR 6CU0 6MGP 6MHR 6MI2	4P6Z
Enriched GO Terms of Interacting Partners?
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