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AP1S1

Description adaptor related protein complex 1 subunit sigma 1
Image
GO Annotations Cellular Component
  • Golgi Membrane
  • Lysosomal Membrane
  • Golgi Apparatus
  • Cytosol
  • Clathrin-coated Pit
  • Membrane
  • AP-1 Adaptor Complex
  • Cytoplasmic Vesicle Membrane
  • Trans-Golgi Network Membrane
  • Intracellular Membrane-bounded Organelle
Molecular Function
Biological Process
  • Intracellular Protein Transport
  • Receptor-mediated Endocytosis
  • Response To Virus
  • Vesicle-mediated Transport
  • Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
  • Regulation Of Defense Response To Virus By Virus
Pathways
  • Nef mediated downregulation of MHC class I complex cell surface expression
  • MHC class II antigen presentation
  • Lysosome Vesicle Biogenesis
  • Golgi Associated Vesicle Biogenesis
Drugs
Diseases
GWAS
  • Adult body size ( 32376654)
Novel Interacting Genes 1 novel interacting genes: TNFRSF9
Interacting Genes 6 interacting genes: AP1G1 AP1G2 AP1M2 AP2A2 PICK1 RHOU
Entrez ID 1174
HPRD ID 04635
Ensembl ID ENSG00000106367
Uniprot IDs A0A024QYT6 P61966
PDB IDs 4P6Z
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025