IL10RB and RCAN1

Data Source:
BioGRID (affinity chromatography technology)

		IL10RB	RCAN1
Description		interleukin 10 receptor subunit beta	regulator of calcineurin 1
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GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Interleukin-28 Receptor Complex	Nucleus Cytoplasm
	Molecular Function	Cytokine Receptor Activity Interleukin-10 Receptor Activity Protein Binding Signaling Receptor Activity	Nucleic Acid Binding Protein Binding Calcium-dependent Protein Serine/threonine Phosphatase Regulator Activity
	Biological Process	Inflammatory Response Immune Response Signal Transduction Cytokine-mediated Signaling Pathway Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Defense Response To Virus	Calcium-mediated Signaling Calcineurin-NFAT Signaling Cascade Regulation Of Phosphoprotein Phosphatase Activity Negative Regulation Of Calcineurin-NFAT Signaling Cascade
Pathways		Other interleukin signaling Interleukin-10 signaling Interleukin-20 family signaling
Drugs			Dipyridamole
Diseases
GWAS		Blood protein levels ( 30072576) Crohn's disease ( 23128233) Multiple sclerosis ( 31604244) Narcolepsy ( 24204295 23459209)	Cancer ( 29299148) Rheumatoid arthritis ( 30423114 23143596 24390342) Rheumatoid arthritis (ACPA-positive) ( 23143596 24532676)
Interacting Genes		7 interacting genes: IFNL2 IFNL3 IL10 IL10RA IL22 UCN2 UCN3	8 interacting genes: APP BTRC GSK3B MAP3K3 MAPK3 PPP3CA USP22 UXT
Entrez ID		3588	1827
HPRD ID		00473	04226
Ensembl ID		ENSG00000243646	ENSG00000159200
Uniprot IDs		Q08334	B7Z1F0 E9PDJ2 P53805 Q6FGP2 Q6ZMM3 V9GYW9
PDB IDs		3LQM 5T5W	6UUQ
Enriched GO Terms of Interacting Partners?
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