IFIT1 and IFIT3

Data Source:
BioGRID (affinity chromatography technology)
HPRD (two hybrid)

		IFIT1	IFIT3
Description		interferon induced protein with tetratricopeptide repeats 1	interferon induced protein with tetratricopeptide repeats 3
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GO Annotations	Cellular Component	Cytoplasm Cytosol Host Cell	Cytoplasm Mitochondrion Cytosol
	Molecular Function	RNA Binding Protein Binding	Molecular_function RNA Binding Protein Binding Identical Protein Binding
	Biological Process	Response To Virus Viral Process Intracellular Transport Of Viral Protein In Host Cell Negative Regulation Of Protein Binding Positive Regulation Of Viral Genome Replication Negative Regulation Of Viral Genome Replication Regulation Of Defense Response To Virus Negative Regulation Of Helicase Activity Defense Response To Virus Type I Interferon Signaling Pathway Cellular Response To Type I Interferon Cellular Response To Exogenous DsRNA	Negative Regulation Of Cell Population Proliferation Response To Virus Cellular Response To Interferon-alpha Negative Regulation Of Apoptotic Process Defense Response To Virus Type I Interferon Signaling Pathway
Pathways		ISG15 antiviral mechanism Interferon alpha/beta signaling	Interferon alpha/beta signaling
Drugs
Diseases
GWAS			Hormone measurements ( 30576415)
Interacting Genes		4 interacting genes: EIF3E IFIT2 IFIT3 IFIT5	20 interacting genes: A2M APOE CYP2C8 DEUP1 ECSIT FANCA HAUS1 IFIT1 IFIT1B IFIT2 IFIT5 LONP1 LVRN MAST1 PSEN2 RAD23A RNF32 TMEM183A TPM1 TPM3
Entrez ID		3434	3437
HPRD ID		00983	05228
Ensembl ID		ENSG00000185745	ENSG00000119917
Uniprot IDs		P09914	O14879 Q5T765
PDB IDs		4HOU 5UDI 5UDJ 5UDK 5UDL 5W5H 5W5I 6C6K	6C6K
Enriched GO Terms of Interacting Partners?
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