GOLGA6A and CDC7

Data Source:
BioGRID (two hybrid)

		GOLGA6A	CDC7
Description		golgin A6 family member A	cell division cycle 7
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Cis Cisterna Cis-Golgi Network Golgi Cisterna Membrane	Nucleus Nucleoplasm Cytoplasm Intercellular Bridge Mitotic Spindle
	Molecular Function	Protein Binding	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Metal Ion Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Golgi Organization Spindle Assembly	G1/S Transition Of Mitotic Cell Cycle Double-strand Break Repair Via Break-induced Replication DNA Replication Positive Regulation Of Cell Population Proliferation Positive Regulation Of Nuclear Cell Cycle DNA Replication Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Peptidyl-serine Phosphorylation Cell Cycle Phase Transition Cell Division Negative Regulation Of G0 To G1 Transition
Pathways			Activation of ATR in response to replication stress Activation of the pre-replicative complex Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS			Eosinophil percentage of white cells ( 27863252) Gestational age at birth (maternal effect) ( 28877031) Glaucoma (primary open-angle) ( 25861811) Lung function (FEV1/FVC) ( 28166213) Lung function (FVC) ( 26635082) Optic disc area ( 25631615 31798171 28073927 21307088) Optic disc parameters ( 20548946) Optic disc size ( 31809533) Optic nerve measurement (cup-to-disc ratio) ( 28061514) Plateletcrit ( 32888494) PR interval ( 32439900) Response to fenofibrate (HDL cholesterol levels) ( 27002377) Vertical cup-disc ratio ( 31798171 25241763 28073927) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		44 interacting genes: ARHGAP9 BAG5 C1orf109 CBY2 CCDC187 CDC7 DEF6 DUSP29 ELOA ENKD1 FAM161B FHL2 GADD45GIP1 HOXB5 IKZF3 KANK2 KCTD9 KDM1A KIF9 KLHL38 MAPK9 MKRN3 MORF4L1 MOS MRPL38 MYOZ1 MYOZ3 NEBL POLR1C PPP2R1A PRKAA2 PSMA1 SPATC1L SYT17 TRAF4 TRAPPC6A TSGA10IP TTC5 TXLNA USP15 USP2 UTP14C YJU2 ZC2HC1C	52 interacting genes: APP BANP CALCOCO2 CDK2 CDK4 CDK9 CDKN1A CDKN2A CHAF1A CLSPN DBF4 DBF4B DIAPH1 DTD1 FXR1 GMEB2 GOLGA2 GOLGA6A GPT GRHPR HMBOX1 HOMEZ IKZF1 IKZF3 IKZF4 LZTS1 MCM10 MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 MEOX2 MTUS2 NDUFB2 ORC1 ORC5 ORC6 PGK1 SERTAD2 STAM2 TMBIM6 TOB1 TRIM27 TRIM37 TSNAXIP1 TSPY10 TSPY3 ZBTB10 ZBTB26 ZBTB8B
Entrez ID		342096	8317
HPRD ID		19190	10345
Ensembl ID		ENSG00000159289	ENSG00000097046
Uniprot IDs		A2VDJ1 Q9NYA3	A0A384MTU6 B2R6V2 O00311
PDB IDs			4F99 4F9A 4F9B 4F9C 5UWQ 5UWR 6YA6 6YA7 6YA8
Enriched GO Terms of Interacting Partners?
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