IDH1 and UBL7

Data Source:
BioGRID (two hybrid)

		IDH1	UBL7
Description		isocitrate dehydrogenase (NADP(+)) 1	ubiquitin like 7
Image
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Mitochondrion Peroxisome Peroxisomal Matrix Cytosol Secretory Granule Lumen Extracellular Exosome Tertiary Granule Lumen Ficolin-1-rich Granule Lumen	Cytosol
	Molecular Function	Magnesium Ion Binding Isocitrate Dehydrogenase (NADP+) Activity Protein Binding Identical Protein Binding Protein Homodimerization Activity Cadherin Binding NADP Binding NAD Binding	Protein Binding Polyubiquitin Modification-dependent Protein Binding
	Biological Process	Glyoxylate Cycle Tricarboxylic Acid Cycle Isocitrate Metabolic Process 2-oxoglutarate Metabolic Process Protein Targeting To Peroxisome NADP Metabolic Process NADPH Regeneration Glutathione Metabolic Process Response To Oxidative Stress Female Gonad Development Neutrophil Degranulation Response To Steroid Hormone Regulation Of Phospholipid Catabolic Process Regulation Of Phospholipid Biosynthetic Process	Ubiquitin-dependent Protein Catabolic Process
Pathways		Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarate NADPH regeneration Neutrophil degranulation Peroxisomal protein import Peroxisomal protein import
Drugs		Isocitric Acid Nicotinamide adenine dinucleotide phosphate Ivosidenib
Diseases
GWAS		Adult diffuse glioma (IDH mutation) ( 32386320) Cerebral amyloid deposition (PET imaging) ( 30361487) Glioma ( 28346443) Non-glioblastoma glioma ( 28346443)	Craniofacial microsomia ( 26853712) Eosinophil percentage of white cells ( 32888494) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Metabolite levels ( 23823483)
Interacting Genes		16 interacting genes: AGGF1 CALM1 CRACR2B DKK3 FAM131A FHL2 FIGNL1 LAX1 LINC01554 NUP62 PEX5 PRDM14 SUMO4 TMOD4 UBL7 ZHX1	16 interacting genes: AP1G1 BAG6 CAPN7 CD4 CDKN2A ERCC1 ESRRG IDH1 MFHAS1 MYBPH NEDD8 RAD23A RXRB SH3GLB1 UBC VBP1
Entrez ID		3417	84993
HPRD ID		00984	16556
Ensembl ID		ENSG00000138413	ENSG00000138629
Uniprot IDs		A0A024R3Y6 O75874	D3DW56 Q96S82
PDB IDs		1T09 1T0L 3INM 3MAP 3MAR 3MAS 4I3K 4I3L 4KZO 4L03 4L04 4L06 4UMX 4UMY 4XRX 4XS3 5DE1 5GIR 5K10 5K11 5L57 5L58 5LGE 5SUN 5SVF 5TQH 5YFM 5YFN 6ADG 6B0Z 6BKX 6BKY 6BKZ 6BL0 6BL1 6BL2 6IO0 6O2Y 6O2Z 6PAY 6Q6F 6U4J 6VEI 6VG0	2CWB 2DEN
Enriched GO Terms of Interacting Partners?
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