TMPRSS11A and ZBTB17

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		TMPRSS11A	ZBTB17
Description		transmembrane serine protease 11A	zinc finger and BTB domain containing 17
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Integral Component Of Plasma Membrane	Nucleoplasm Protein-containing Complex Protein-DNA Complex
	Molecular Function	Serine-type Endopeptidase Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Core Promoter Sequence-specific DNA Binding Transcription Coactivator Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Transcription Factor Binding Metal Ion Binding
	Biological Process	Proteolysis Cell Cycle	Negative Regulation Of Transcription By RNA Polymerase II Gastrulation With Mouth Forming Second Regulation Of Transcription By RNA Polymerase II Ectoderm Development Negative Regulation Of Cell Population Proliferation IRE1-mediated Unfolded Protein Response Negative Regulation Of Cell Cycle Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Cell Cycle Arrest
Pathways			XBP1(S) activates chaperone genes
Drugs
Diseases
GWAS		Regular attendance at a pub or social club ( 29970889)	Erectile dysfunction ( 30583798) Glomerular filtration rate ( 29403010) Heel bone mineral density ( 30598549) Idiopathic dilated cardiomyopathy ( 21459883)
Interacting Genes		3 interacting genes: ACE2 SRPK2 ZBTB17	27 interacting genes: BCL6 CDKN2B CREBBP DIS3 DNMT3A E2F6 EP300 ESR1 ESR2 GTF2I HCFC1 HK2 HK3 HSPB1 IRF8 ITGB5 MAX MSX2 MYC MYCN PGR TMPRSS11A TOPBP1 TRIM55 TRIM63 ZBTB7C ZBTB8A
Entrez ID		339967	7709
HPRD ID		07123	04968
Ensembl ID		ENSG00000187054	ENSG00000116809
Uniprot IDs		A0A0A0MR82 A8KA85 Q6ZMR5	Q13105 Q53EM1
PDB IDs			2LVR 2LVT 2LVU 2M0D 2M0E 2M0F 2N25 2N26 2Q81 3M52 4U2M 4U2N 5ION
Enriched GO Terms of Interacting Partners?
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