APOBEC1 and CACNA1I

Data Source:
BioGRID (biochemical)

		APOBEC1	CACNA1I
Description		apolipoprotein B mRNA editing enzyme catalytic subunit 1	calcium voltage-gated channel subunit alpha1 I
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm	Voltage-gated Sodium Channel Complex Voltage-gated Calcium Channel Complex Neuron Projection
	Molecular Function	RNA Binding MRNA Binding Cytidine Deaminase Activity Cytosine Deaminase Activity Protein Binding Enzyme Activator Activity Zinc Ion Binding Protein Domain Specific Binding Ribonucleoprotein Complex Binding	Voltage-gated Calcium Channel Activity Voltage-gated Sodium Channel Activity Protein Binding Low Voltage-gated Calcium Channel Activity
	Biological Process	RNA Processing MRNA Processing Lipid Metabolic Process Response To Osmotic Stress Cytidine Deamination Response To Zinc Ion Cytidine To Uridine Editing MRNA Modification Cellular Response To Insulin Stimulus Response To Drug Response To Ethanol Regulation Of Catalytic Activity Response To Calcium Ion Defense Response To Virus DNA Cytosine Deamination DNA Demethylation Negative Regulation Of DNA Methylation-dependent Heterochromatin Assembly Positive Regulation Of MRNA Modification	Signal Transduction Neuronal Action Potential Flagellated Sperm Motility Sleep Regulation Of Ion Transmembrane Transport Sodium Ion Transmembrane Transport Positive Regulation Of Calcium Ion-dependent Exocytosis Calcium Ion Import Calcium Ion Transmembrane Transport Membrane Depolarization During Action Potential
Pathways		mRNA Editing: C to U Conversion Formation of the Editosome	NCAM1 interactions
Drugs		Zinc chloride Zinc sulfate, unspecified form	Ergocalciferol Enflurane Amlodipine Spironolactone Cinnarizine Paramethadione Zonisamide Nifedipine Amiodarone Mibefradil Flunarizine Nylidrin Cannabidiol Trimebutine Benidipine Efonidipine Manidipine Butamben Bioallethrin Bioallethrin Medical Cannabis Nabiximols
Diseases
GWAS		Body mass index ( 28552196) Creatine kinase levels ( 29403010) HDL cholesterol levels ( 28334899)	anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Cognitive ability (MTAG) ( 29186694) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Household income (MTAG) ( 31844048) IgG glycosylation ( 23382691) Intelligence (MTAG) ( 29326435) Negative urgency ( 30718321) Refractive error ( 32231278) Response to methotrexate in juvenile idiopathic arthritis ( 24709693) Schizophrenia ( 28991256 22883433 29483656 30285260)
Interacting Genes		16 interacting genes: A1CF APOBEC2 BAG4 CDK6 CELF2 DNAJB11 DND1 HNRNPF HNRNPK KPNA2 KRTAP19-5 KRTAP6-1 KRTAP6-2 NOTO SYNCRIP UFSP2
Entrez ID		339	8911
HPRD ID		02531	10500
Ensembl ID		ENSG00000111701	ENSG00000100346
Uniprot IDs		P41238	Q9P0X4
PDB IDs
Enriched GO Terms of Interacting Partners?
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