KRTAP21-2 and NTN4

Data Source:
BioGRID (two hybrid)

		KRTAP21-2	NTN4
Description		keratin associated protein 21-2	netrin 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament	Plasma Membrane Laminin Complex
	Molecular Function	Protein Binding	Protein Binding Laminin-1 Binding
	Biological Process	Keratinization	Axon Guidance Animal Organ Morphogenesis Tissue Development Neuron Remodeling Cell Migration Substrate Adhesion-dependent Cell Spreading Regulation Of Branching Involved In Salivary Gland Morphogenesis By Extracellular Matrix-epithelial Cell Signaling Basement Membrane Assembly
Pathways		Keratinization	Non-integrin membrane-ECM interactions Netrin-1 signaling
Drugs
Diseases
GWAS			3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Allergic dermatitis (nickel) ( 23921680) Blood protein levels ( 30072576 29875488) BRCA1/2-negative high-risk breast cancer ( 30323354) Breast cancer ( 29059683 23535729 23535733) Breast size ( 27182965) Diastolic blood pressure ( 30224653) Diffusing capacity of carbon monoxide ( 30694715) Refractive error ( 32231278)
Interacting Genes		30 interacting genes: ADAMTSL4 ATXN1L BEX2 CLCNKA DMRTB1 EFEMP1 FAM221A FOXD2 GATA2 KRTAP10-1 KRTAP12-2 KRTAP26-1 LCE1A LCE2A LCE5A MKRN3 NTN4 PLSCR4 POU4F2 PRR13 RNF38 RNF44 SMARCC1 SMN1 SMN2 SNRPC SPAG8 TCF7L2 VENTX ZIC1	13 interacting genes: ADAMTSL4 CASK CYSRT1 HOXA1 KPRP KRTAP10-8 KRTAP21-2 KRTAP5-9 LCE1C MEOX2 NBPF19 NOTCH2NLA PLSCR1
Entrez ID		337978	59277
HPRD ID		11215	10121
Ensembl ID		ENSG00000187026	ENSG00000074527
Uniprot IDs		Q3LI59	A8K3H6 B2RE43 Q9HB63
PDB IDs
Enriched GO Terms of Interacting Partners?
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