UBAC2 and LMO7

Data Source:
HPRD (two hybrid)

		UBAC2	LMO7
Description		UBA domain containing 2	LIM domain 7
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane	Ubiquitin Ligase Complex Nucleus Nuclear Envelope Cytoplasm Cytosol Focal Adhesion Cell Surface Apical Plasma Membrane
	Molecular Function	Protein Binding	Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding
	Biological Process	Wnt Signaling Pathway Protein Localization To Endoplasmic Reticulum Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Retrograde Protein Transport, ER To Cytosol	Protein Polyubiquitination Protein Ubiquitination Regulation Of Signaling Regulation Of Cell Adhesion Post-translational Protein Modification Positive Regulation Of Transcription By RNA Polymerase II
Pathways			Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Asthma ( 31361310 31959851 30929738 32296059 31619474) Asthma (childhood onset) ( 31036433 30929738) Basal cell carcinoma ( 21700618) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Cuneus cortex volume ( 31530798) Eosinophil counts ( 32888494 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Inflammatory bowel disease ( 28067908) Medication use (adrenergics, inhalants) ( 31015401) Metabolite levels ( 23823483) Neutrophil percentage of granulocytes ( 27863252) Psoriasis ( 28537254) Sum eosinophil basophil counts ( 27863252) Systemic lupus erythematosus ( 33536424)	Cutaneous melanoma or hair colour ( 32341527) Glaucoma (multi-trait analysis) ( 31959993) Glaucoma (primary open-angle) ( 29449654) Initial pursuit acceleration ( 29064472) Initial pursuit acceleration in psychotic disorders ( 29064472) Intraocular pressure ( 29617998 29785010 31959993 30054594) Mean corpuscular hemoglobin ( 32888494) Multiple system atrophy (pathologically confirmed) ( 27629089) Obsessive-compulsive disorder ( 30456828) Type 1 diabetes ( 21980299)
Interacting Genes		4 interacting genes: CALCOCO2 GET4 LMO7 UBC	11 interacting genes: ABCA1 CALM1 EMD MDM2 PKM RHOU SRPK2 SUMO2 UBAC2 YWHAG YWHAQ
Entrez ID		337867	4008
HPRD ID		11429	05078
Ensembl ID		ENSG00000134882	ENSG00000136153
Uniprot IDs		A0A024RE02 A8K2S7 Q8NBM4	A0A0A0MTE2 E9PMT2 F8J2B5 F8WD26 Q8WWI1
PDB IDs			2EAQ
Enriched GO Terms of Interacting Partners?
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