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HSPD1 and LINC01554
Data Source:
BioGRID
(unspecified method)
HSPD1
LINC01554
Description
heat shock protein family D (Hsp60) member 1
long intergenic non-protein coding RNA 1554
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Space
Cytoplasm
Mitochondrion
Mitochondrial Inner Membrane
Mitochondrial Matrix
Early Endosome
Cytosol
Plasma Membrane
Clathrin-coated Pit
Cell Surface
Membrane
Coated Vesicle
Secretory Granule
Protein-containing Complex
Lipopolysaccharide Receptor Complex
Extracellular Exosome
Molecular Function
Lipopolysaccharide Binding
P53 Binding
DNA Replication Origin Binding
Single-stranded DNA Binding
RNA Binding
Double-stranded RNA Binding
Protein Binding
ATP Binding
High-density Lipoprotein Particle Binding
Isomerase Activity
ATPase Activity
Enzyme Binding
Ubiquitin Protein Ligase Binding
Apolipoprotein Binding
Apolipoprotein A-I Binding
Unfolded Protein Binding
Chaperone Binding
Biological Process
MyD88-dependent Toll-like Receptor Signaling Pathway
Positive Regulation Of T Cell Mediated Immune Response To Tumor Cell
Regulation Of Transcription By RNA Polymerase II
Protein Folding
'de Novo' Protein Folding
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Response To Unfolded Protein
Apoptotic Mitochondrial Changes
Response To Cold
Viral Process
Positive Regulation Of Interferon-alpha Production
Positive Regulation Of Interferon-gamma Production
Positive Regulation Of Interleukin-10 Production
Positive Regulation Of Interleukin-12 Production
Positive Regulation Of Interleukin-6 Production
Mitochondrial Unfolded Protein Response
Protein Refolding
B Cell Proliferation
T Cell Activation
B Cell Activation
Positive Regulation Of Macrophage Activation
Positive Regulation Of Apoptotic Process
Negative Regulation Of Apoptotic Process
Adhesion Of Symbiont To Host
Protein Import Into Mitochondrial Intermembrane Space
Isotype Switching To IgG Isotypes
Protein Stabilization
Positive Regulation Of T Cell Activation
Chaperone-mediated Protein Complex Assembly
Protein Maturation
Biological Process Involved In Interaction With Symbiont
Pathways
Mitochondrial protein import
Mitochondrial protein import
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation
Drugs
Copper
Diseases
Hereditary spastic paraplegia (SPG)
Hypomyelinating leukodystrophy (HLD); Pelizaeus-Merzbacher disease (PMD)
GWAS
Autism spectrum disorder or schizophrenia (
28540026
)
Brain morphology (min-P) (
32665545
)
Brain morphology (MOSTest) (
32665545
)
Cortical surface area (MOSTest) (
32665545
)
Cortical thickness (MOSTest) (
32665545
)
Schizophrenia (
25056061
29483656
)
Subcortical volume (min-P) (
32665545
)
Subcortical volume (MOSTest) (
32665545
)
Interacting Genes
54 interacting genes:
ALDH2
APP
BAK1
BRCA1
CA2
CASP3
CASP9
CEP70
CLEC7A
CLU
CYSRT1
DHFR
DUX4
ERBB2
ERG
FAM107A
FHIT
H2BC21
HSPE1
ITGA3
ITGB1
KRT31
KRT34
KRT40
KRTAP10-3
KRTAP10-8
KRTAP5-9
LINC01554
LRRK2
LZTS2
MAPK6
MCPH1
NOS1AP
NOTCH2NLA
NR3C1
PLCG2
PLG
PPP2R1A
PPP2R1B
PRKACA
PRNP
PTEN
PTPN11
RASA1
RGS20
SAMD3
SUMO2
SUMO4
SUPT6H
TLR1
TMCC2
TRIM63
UBASH3A
YWHAG
141 interacting genes:
AARS1
ACADVL
ACIN1
ACTB
ACTG1
ACTN1
ACTN3
ACTR3
ALDOA
ANXA2
ANXA5
ANXA6
APEX1
ARHGAP1
ASS1
ATAD3A
ATIC
ATP5F1A
BZW2
CANX
CCT2
CCT3
CCT4
CCT6A
CCT7
CKAP4
CS
CTPS1
DDX3X
DDX46
DHX9
DNAH2
DNAJA1
DST
DYNC1H1
EDARADD
EEF1G
EEF2
EIF3A
EIF3E
EIF4A2
EIF4B
ENO1
ENO3
EPRS1
ERO1A
G3BP1
G6PD
GANAB
GAPDH
GARS1
GDI2
GPI
GTF2I
HIVEP2
HMCN1
HNRNPF
HSP90AA1
HSP90B1
HSPA1L
HSPA5
HSPA8
HSPA9
HSPD1
HYOU1
IDH1
IPO4
IPO7
IPO9
ITPR2
KARS1
KPNA1
KPNB1
KRT18
KRT7
KRT8
KRT8P3
LRPPRC
MCM7
MSN
MYO18A
NAP1L1
NAP1L4
NCBP1
NCL
NPM1
OLA1
OXCT1
PABPC1
PCBP2
PDIA3
PDIA6
PFAS
PGD
PGK1
PGM1
PHGDH
PKM
PLOD2
PMPCA
POR
PPP2R1A
PSMC1
PSMD2
PSMD7
PTBP1
RDX
RPL6
RPSA
RTCB
RTN4
SARS1
SEPTIN7
SEPTIN9
SERPINH1
SFPQ
SQSTM1
TARS1
TGFBI
THOP1
TKT
TTF2
TUBA1A
TUBA8
TUBB
TUBB2A
TUBB3
TUBB4A
TUBB4B
TUBB6
TUFM
TXNRD1
TYMP
UBA1
VCL
VCP
VIM
VPS35
WARS1
XPO1
XRCC5
Entrez ID
3329
202299
HPRD ID
00318
16896
Ensembl ID
ENSG00000144381
ENSG00000236882
Uniprot IDs
A0A024R3X4
P10809
PDB IDs
4PJ1
6HT7
6MRC
6MRD
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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