HOXC11 and TRIP10

Data Source:
BioGRID (two hybrid)

		HOXC11	TRIP10
Description		homeobox C11	thyroid hormone receptor interactor 10
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytosol	Phagocytic Cup Nucleoplasm Cytoplasm Lysosome Golgi Apparatus Cytosol Cytoskeleton Cell Cortex Cell Projection Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Sequence-specific Double-stranded DNA Binding	Protein Binding Lipid Binding Identical Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Multicellular Organism Development Endoderm Development Positive Regulation Of Transcription By RNA Polymerase II Anatomical Structure Development	Endocytosis Cell Communication Signal Transduction Actin Cytoskeleton Organization Regulation Of Small GTPase Mediated Signal Transduction Membrane Organization
Pathways			Rho GTPase cycle Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		16 interacting genes: CD2AP DNMT3L GTF2A1L GTF2H1 HDAC5 HTT IRF4 MEIS1 PSMA1 RCHY1 SMAD3 SOX8 SP1 STAT3 TBX21 TRIP10	41 interacting genes: ABI1 ABL2 AKAP9 ARHGAP12 ARHGAP17 CDC42 CREBBP CTNNB1 DNM2 DTX3 HOXC11 HTT JRK LYN MEOX1 MEOX2 NKX2-5 PAX6 PDE6G POT1 PRKACA RHOJ RHOQ RIN1 RXRA SF3A2 SH3BP1 SMARCE1 SMURF1 SRC STAT3 TERF1 THAP1 THRB TINF2 UTF1 WAS WASF1 WASL WBP11 ZBTB7B
Entrez ID		3227	9322
HPRD ID		09275	05142
Ensembl ID		ENSG00000123388	ENSG00000125733
Uniprot IDs		O43248	Q15642 W4VSQ9
PDB IDs			2CT4 2EFK 2KE4
Enriched GO Terms of Interacting Partners?
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