HOXC9 and ELAVL2

Data Source:
BioGRID (two hybrid)

		HOXC9	ELAVL2
Description		homeobox C9	ELAV like RNA binding protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Aggresome	Nucleoplasm Ribonucleoprotein Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding	RNA Binding MRNA 3'-UTR Binding Protein Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Anterior/posterior Pattern Specification Proximal/distal Pattern Formation Embryonic Skeletal System Morphogenesis	MRNA Splicing, Via Spliceosome Regulation Of Transcription, DNA-templated
Pathways			mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Heel bone mineral density ( 30598549) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Asthma ( 30929738) Asthma (childhood onset) ( 30929738) Asthma onset (childhood vs adult) ( 30929738) Body mass index ( 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically inactive individuals ( 28448500) Chronic obstructive pulmonary disease ( 30804561) Feeling guilty ( 29500382) Fulminant type 1 diabetes ( 30552108) General cognitive ability ( 29844566) Glomerular filtration rate change in heart transplantation ( 30160337) Insomnia symptoms (never/rarely vs. sometimes/usually) ( 30804566) Insomnia symptoms (never/rarely vs. usually) ( 30804566) Intelligence (MTAG) ( 29326435) Lung function (FEV1/FVC) ( 30061609) Neurociticism ( 29500382) Neuroticism ( 27089181 29255261 27067015) Physiological traits ( 31902109) Plasma t-tau levels ( 28100725) Remission after SSRI treatment in MDD or neuroticism ( 29559929)
Interacting Genes		29 interacting genes: CBX6 CYSRT1 ELAVL2 GMNN GTF2A1L HOXC13 HOXD1 HOXD9 IRF9 KRTAP6-2 LPXN MAGED1 MSX2 NFKBID NMI PAX6 PAX8 PBX2 PCGF2 POLR2D POLR3D POU2AF1 POU2F1 TEX37 TLE5 UFSP1 ZFP36 ZMYND12 ZNF384	6 interacting genes: ELAVL3 ELAVL4 HNRNPAB HOXC9 NR2E3 RBFOX2
Entrez ID		3225	1993
HPRD ID		00857	03396
Ensembl ID		ENSG00000180806	ENSG00000107105
Uniprot IDs		A0A024RAZ6 P31274	A0A0A0MRX1 Q12926
PDB IDs		2LP0 2MSY
Enriched GO Terms of Interacting Partners?
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