HNRNPL and HMG20B

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		HNRNPL	HMG20B
Description		heterogeneous nuclear ribonucleoprotein L	high mobility group 20B
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Membrane Ribonucleoprotein Granule Extracellular Exosome Ribonucleoprotein Complex	Nucleus Nucleoplasm Chromosome Nuclear Body
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding RNA Binding MRNA Binding Protein Binding Pre-mRNA Intronic Binding	DNA Binding Protein Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome RNA Processing RNA Metabolic Process Regulation Of RNA Splicing	Chromatin Organization Cell Cycle Blood Coagulation Regulation Of Gene Expression Negative Regulation Of Protein Sumoylation Skeletal Muscle Cell Differentiation Positive Regulation Of Neuron Differentiation
Pathways		mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA	HDACs deacetylate histones Potential therapeutics for SARS Factors involved in megakaryocyte development and platelet production
Drugs		Copper
Diseases
GWAS		Anti-saccade response ( 29064472) Logical memory (immediate recall) in mild cognitive impairment ( 29274321)
Interacting Genes		89 interacting genes: APEX1 CSE1L CSNK2A1 FGFR3 H3-4 HMG20B HMGA1 HNRNPA2B1 HNRNPK IL7R ITCH MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I NEDD4 PCBP2 PJA1 PTBP1 SUMO2 SUMO4	28 interacting genes: APP BRCA2 C14orf119 CCDC102B CCDC136 CCDC85B E2F6 ERP29 FBXO7 HMG20A HNRNPL KIF4A KRT15 KRT38 MID1 NKX3-1 NUTF2 PHF21A PIAS2 PPP1R13B SNAPC5 SYCE1 TACC2 TFIP11 TRAF1 USHBP1 VIM WAC
Entrez ID		3191	10362
HPRD ID		04360	05703
Ensembl ID		ENSG00000104824	ENSG00000064961
Uniprot IDs		P14866 Q6NTA2	Q9P0W2
PDB IDs		3R27 3TO8
Enriched GO Terms of Interacting Partners?
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