HMMR and NAT2

Data Source:
BioGRID (two hybrid)

		HMMR	NAT2
Description		hyaluronan mediated motility receptor	N-acetyltransferase 2
Image		No pdb structure
GO Annotations	Cellular Component	Centrosome Cytosol Plasma Membrane Cell Surface Microtubule Cytoskeleton Membrane	Cytosol
	Molecular Function	Protein Binding Hyaluronic Acid Binding	Arylamine N-acetyltransferase Activity Protein Binding
	Biological Process	Regulation Of G2/M Transition Of Mitotic Cell Cycle Hyaluronan Catabolic Process	Xenobiotic Metabolic Process
Pathways		Hyaluronan uptake and degradation AURKA Activation by TPX2	Acetylation
Drugs		Hyaluronic acid
Diseases
GWAS		Metabolite levels ( 23823483)	Apolipoprotein A1 levels ( 32203549) Apolipoprotein B levels ( 32203549) Bladder cancer ( 24163127 20972438) Blood metabolite levels ( 24816252) Blood metabolite ratios ( 24816252) Cholesterol, total ( 24097068 20686565) Coronary artery disease ( 29212778 33020668) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Insulin resistance/response ( 25798622) Iron status biomarkers (transferrin levels) ( 25352340) LDL cholesterol levels ( 32203549) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Liver injury in anti-tuberculosis drug treatment ( 31109976) Medication use (calcium channel blockers) ( 31015401) Medication use (HMG CoA reductase inhibitors) ( 31015401) Metabolic syndrome ( 31589552) Metabolic traits ( 21886157) Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917) Paclitaxel-induced neuropathy ( 23776197) Total cholesterol levels ( 28334899) Triglyceride levels ( 32203549 28334899 29403010 30698716) Triglyceride levels in current drinkers ( 30698716) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Triglyceride levels x long total sleep time interaction (2df test) ( 31719535) Triglyceride levels x short total sleep time interaction (2df test) ( 31719535) Triglycerides ( 24097068 20686565) Urinary metabolite levels in chronic kidney disease ( 31959995) Urinary metabolite modules (eigenmetabolites) in chronic kidney disease ( 31959995) Urinary metabolites ( 26352407 21572414) Urinary metabolites (H-NMR features) ( 24586186) Youthful appearance (self-reported) ( 32339537)
Interacting Genes		16 interacting genes: ACTB BACH1 CALM1 CD44 CDH13 GREB1 IL24 ITIH5 MAPK3 MORN4 NAT2 SVIL THRSP TPX2 TRIM54 TUBB2A	17 interacting genes: APC APP AURKA BAG4 CDKN2A CDKN2C ERBB2 FZR1 HMMR IGF1R MBD4 NAA10 NBN PALB2 PPM1D STK11 WT1
Entrez ID		3161	10
HPRD ID		02963	02000
Ensembl ID		ENSG00000072571	ENSG00000156006
Uniprot IDs		O75330	A4Z6T7 P11245
PDB IDs			2PFR
Enriched GO Terms of Interacting Partners?
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