HMGCS2 and ERO1B

Data Source:
BioGRID (affinity chromatography technology)

		HMGCS2	ERO1B
Description		3-hydroxy-3-methylglutaryl-CoA synthase 2	endoplasmic reticulum oxidoreductase 1 beta
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix	Endoplasmic Reticulum Endoplasmic Reticulum Membrane
	Molecular Function	Hydroxymethylglutaryl-CoA Synthase Activity Identical Protein Binding	Protein Disulfide Isomerase Activity Protein Binding Protein Disulfide Oxidoreductase Activity Oxidoreductase Activity Oxidoreductase Activity, Acting On A Sulfur Group Of Donors, Disulfide As Acceptor Thiol Oxidase Activity Unfolded Protein Binding
	Biological Process	Acetyl-CoA Metabolic Process Cholesterol Biosynthetic Process Farnesyl Diphosphate Biosynthetic Process, Mevalonate Pathway Regulation Of Lipid Metabolic Process Ketone Body Biosynthetic Process	Protein Folding Protein Phosphopantetheinylation Protein Folding In Endoplasmic Reticulum
Pathways		PPARA activates gene expression Synthesis of Ketone Bodies	Insulin processing
Drugs			1-Ethyl-Pyrrolidine-2,5-Dione Flavin adenine dinucleotide
Diseases		HMG-CoA synthase (HMGCS) deficiency
GWAS		Change in glucose in response to thiazide diuretic treatment in hypertension ( 29523524) Metabolite levels ( 23823483)
Interacting Genes		3 interacting genes: APP FBXO7 HSD17B10	3 interacting genes: BRCA1 ERP44 P4HB
Entrez ID		3158	56605
HPRD ID		02580	13279
Ensembl ID		ENSG00000134240	ENSG00000086619
Uniprot IDs		A0A140VJL2 P54868	Q86YB8
PDB IDs		2WYA
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?