HLX and MIEN1

Data Source:
BioGRID (two hybrid)

		HLX	MIEN1
Description		H2.0 like homeobox	migration and invasion enhancer 1
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Nucleoplasm Cytosol Plasma Membrane Intrinsic Component Of The Cytoplasmic Side Of The Plasma Membrane Centriolar Satellite
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Sequence-specific DNA Binding	Protein Binding
	Biological Process	Liver Development Regulation Of Transcription By RNA Polymerase II Multicellular Organism Development Skeletal Muscle Tissue Development Positive Regulation Of Cell Population Proliferation Cell Differentiation Positive Regulation Of T-helper 1 Cell Differentiation Negative Regulation Of T-helper 2 Cell Differentiation Positive Regulation Of Organ Growth Enteric Nervous System Development Embryonic Digestive Tract Morphogenesis	Apoptotic Process Response To Selenium Ion Positive Regulation Of Cell Migration Negative Regulation Of Apoptotic Process Positive Regulation Of Filopodium Assembly
Pathways
Drugs
Diseases
GWAS		Apolipoprotein B levels ( 32203549) C-reactive protein levels or total cholesterol levels (pleiotropy) ( 27286809) Cerebrospinal fluid AB1-42 levels ( 26252872) Diverticular disease ( 30177863) Eosinophil percentage of white cells ( 32888494) FEV1 ( 30804560) Granulocyte percentage of myeloid white cells ( 27863252) Lung function (FVC) ( 30804560) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Monocyte percentage of white cells ( 32888494 27863252) Neutrophil count ( 32888494) Obesity-related traits ( 23251661) PR interval ( 32439900) Triglyceride levels ( 32154731) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for body mass index ( 25673412) White blood cell count ( 32888494)	Asthma ( 31619474 29273806) Asthma or allergic disease (pleiotropy) ( 29785011) Systemic lupus erythematosus ( 28714469)
Interacting Genes		13 interacting genes: ATXN1L C14orf119 CALCOCO2 CYSRT1 DTX2 FOXH1 LONRF1 MIEN1 PRR20A PRR20B PRR20C PRR20D PRR20E	14 interacting genes: ARID5A DDIT4L GORASP2 HDAC7 HIVEP1 HLX HMGB2 NLGN3 POU6F2 REL RNF126 TRIP6 VENTX ZBTB32
Entrez ID		3142	84299
HPRD ID		00875	12681
Ensembl ID		ENSG00000136630	ENSG00000141741
Uniprot IDs		Q14774	J3KTI2 Q9BRT3
PDB IDs			2LJK
Enriched GO Terms of Interacting Partners?
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