KCNIP1 and KCND3

Data Source:
BioGRID (pull down)

		KCNIP1	KCND3
Description		potassium voltage-gated channel interacting protein 1	potassium voltage-gated channel subfamily D member 3
Image
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Voltage-gated Potassium Channel Complex Dendrite Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane	Plasma Membrane Voltage-gated Potassium Channel Complex Postsynaptic Density Integral Component Of Membrane Sarcolemma Neuronal Cell Body Dendritic Spine Postsynaptic Membrane GABA-ergic Synapse Integral Component Of Postsynaptic Specialization Membrane
	Molecular Function	Voltage-gated Ion Channel Activity Potassium Channel Activity Calcium Ion Binding Protein Binding Potassium Channel Regulator Activity	Voltage-gated Potassium Channel Activity A-type (transient Outward) Potassium Channel Activity Protein Binding Ion Channel Binding Metal Ion Binding Voltage-gated Potassium Channel Activity Involved In Cardiac Muscle Cell Action Potential Repolarization Voltage-gated Potassium Channel Activity Involved In Ventricular Cardiac Muscle Cell Action Potential Repolarization
	Biological Process	Cardiac Conduction Potassium Ion Transmembrane Transport Regulation Of Potassium Ion Transmembrane Transport	Potassium Ion Transport Regulation Of Ion Transmembrane Transport Protein Homooligomerization Cardiac Conduction Potassium Ion Transmembrane Transport Membrane Repolarization Membrane Repolarization During Cardiac Muscle Cell Action Potential Regulation Of Heart Rate By Cardiac Conduction Potassium Ion Export Across Plasma Membrane Membrane Repolarization During Ventricular Cardiac Muscle Cell Action Potential Ventricular Cardiac Muscle Cell Membrane Repolarization
Pathways		Phase 1 - inactivation of fast Na+ channels	Voltage gated Potassium channels Phase 1 - inactivation of fast Na+ channels
Drugs			Enflurane Disopyramide Imipramine Promethazine Miconazole Nifedipine Dronedarone Vernakalant Dalfampridine Isavuconazole
Diseases
GWAS		Acne (severe) ( 24927181) California verbal learning test score ( 31596458) Liver transplant-free survival in primary sclerosing cholangitis (time to event) ( 28779025) Normalized brain volume ( 19010793) Placental abruption ( 29884306) Pre-treatment viral load in HIV-1 infection ( 31219150) Short-term memory (digit-span task) ( 30741946)	Adult body size ( 32376654) Atrial fibrillation ( 28416822 30061737 29892015) Early cardiac repolarization ( 31600170 22683750) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Immune reponse to smallpox (secreted IFN-alpha) ( 22610502) Medication use (opioids) ( 31015401) Multisite chronic pain ( 31194737) P wave duration ( 24850809) P wave terminal force ( 28794112) PR interval ( 30679814 32439900) Response to radiotherapy in cancer (late toxicity) ( 24785509) TPE interval (resting) ( 32386560) Visceral adipose tissue adjusted for BMI ( 22589738)
Interacting Genes		16 interacting genes: AMPD3 ASPH CIAO2A DAAM2 IL6ST KCND1 KCND2 KCND3 KCNIP2 LITAF NHLH2 NIF3L1 SOD3 SPP1 SPRED2 TBC1D25	2 interacting genes: KCNIP1 KCNIP2
Entrez ID		30820	3752
HPRD ID		06879	16104
Ensembl ID		ENSG00000182132	ENSG00000171385
Uniprot IDs		Q9NZI2	A0A024R0C6 Q9UK17
PDB IDs		1S1E 2I2R 2NZ0	1S1G 2NZ0
Enriched GO Terms of Interacting Partners?
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