HELLS and SERTAD2

Data Source:
BioGRID (two hybrid)

		HELLS	SERTAD2
Description		helicase, lymphoid specific	SERTA domain containing 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Nucleus Pericentric Heterochromatin	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Chromatin Binding Helicase Activity Protein Binding ATP Binding	Transcription Coactivator Activity Protein Binding Transcription Regulator Activity
	Biological Process	DNA Methylation DNA Methylation-dependent Heterochromatin Assembly Cell Cycle Multicellular Organism Development Maintenance Of DNA Methylation Pericentric Heterochromatin Assembly Lymphocyte Proliferation Cell Division	Negative Regulation Of Cell Growth Chromatin-mediated Maintenance Of Transcription
Pathways
Drugs
Diseases
GWAS		Plasma clozapine-norclozapine ratio in treatment-resistant schizophrenia ( 30922102) Red cell distribution width ( 32888494) Response to (pegylated) interferon in chronic hepatitis B ( 30715261) Thiopurine-induced alopecia in inflammatory bowel disease ( 29923122) Warfarin maintenance dose (adjusted for clinical factors) ( 28686080)	Antisaccade task score ( 31596458) Apolipoprotein B levels ( 32203549) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Heel bone mineral density ( 30598549) LDL cholesterol levels ( 32203549) Low density lipoprotein cholesterol levels ( 32154731) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular volume ( 29403010 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte percentage of white cells ( 32888494 27863252) Plateletcrit ( 32888494) Red blood cell count ( 32888494) Red cell distribution width ( 32888494 27863252 28957414) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) TPE interval (resting) ( 32386560) Visceral fat ( 22589738)
Interacting Genes		9 interacting genes: - APP DNMT1 DNMT3B E2F3 GTSF1L HDAC1 MEOX2 SERTAD2	25 interacting genes: ATG12 C1orf109 CDC7 CKS1B CREBBP CTNNA3 E2F1 ESPNL HELLS IGFN1 KAT2B KAT5 PARVG PIK3R3 PLA2G6 PRKAB2 STRA8 SUPT7L TFDP1 TNS2 TRIM28 XPO1 ZNF524 ZNF581 ZSCAN22
Entrez ID		3070	9792
HPRD ID		07232	18040
Ensembl ID		ENSG00000119969	ENSG00000179833
Uniprot IDs		A0A087WSW7 A0A0B4J1V9 F6XU50 Q0VGL2 Q76H82 Q9NRZ9	Q14140
PDB IDs
Enriched GO Terms of Interacting Partners?
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