TBX21 and ZNF490

Data Source:
BioGRID (two hybrid)

		TBX21	ZNF490
Description		T-box transcription factor 21	zinc finger protein 490
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Neuronal Cell Body	Nucleus
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Cell Fate Specification Heart Looping Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Multicellular Organism Development Response To Virus T Cell Differentiation Negative Regulation Of Interleukin-2 Production Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of T Cell Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Isotype Switching To IgG Isotypes Cellular Response To Organic Substance Lymphocyte Migration Negative Regulation Of T-helper 17 Cell Differentiation Negative Regulation Of T-helper 17 Cell Lineage Commitment Negative Regulation Of T-helper 2 Cell Cytokine Production	Regulation Of Transcription By RNA Polymerase II
Pathways			Generic Transcription Pathway
Drugs
Diseases
GWAS		Ankylosing spondylitis ( 23749187) Asthma ( 30929738 31619474) Asthma (childhood onset) ( 31036433) Autoimmune thyroid disease ( 32581359) Body mass index ( 26426971 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically inactive individuals ( 28448500) Brain morphology (MOSTest) ( 32665545) Diverticular disease ( 30177863) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Multiple sclerosis ( 22190364) Simvastatin-induced myopathy ( 31220337)	Adult body size ( 32376654)
Interacting Genes		3 interacting genes: EXOC5 HOXC11 ZNF490	34 interacting genes: CCDC136 CCNDBP1 CEP70 DTNBP1 FSD2 GLRX3 GOLGA6L9 HAP1 HOXB13 KRT40 KRTAP10-3 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP12-3 LMNA LZTR1 LZTS2 MDFI MEOX2 MTUS2 NDEL1 RBMX RNPS1 STX1A TBX21 TEX19 TRAF1 TRIM41 TSGA10 VWC2 ZBTB32 ZC4H2 ZRANB1
Entrez ID		30009	57474
HPRD ID		05355	15802
Ensembl ID		ENSG00000073861	ENSG00000188033
Uniprot IDs		Q9UL17	Q9ULM2
PDB IDs
Enriched GO Terms of Interacting Partners?
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