TRHDE and REG3A

Data Source:
HPRD (two hybrid, in vitro)

		TRHDE	REG3A
Description		thyrotropin releasing hormone degrading enzyme	regenerating family member 3 alpha
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Extracellular Exosome	Extracellular Region Extracellular Space Cytoplasm
	Molecular Function	Aminopeptidase Activity Zinc Ion Binding Peptide Binding Metalloaminopeptidase Activity	Protein Binding Carbohydrate Binding Signaling Receptor Activity Identical Protein Binding Peptidoglycan Binding Oligosaccharide Binding
	Biological Process	Proteolysis Signal Transduction Cell-cell Signaling Regulation Of Blood Pressure Peptide Catabolic Process	Acute-phase Response Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Positive Regulation Of Cell Population Proliferation Positive Regulation Of Keratinocyte Proliferation Antimicrobial Humoral Response Response To Peptide Hormone Cell Wall Disruption In Other Organism Negative Regulation Of Keratinocyte Differentiation Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Positive Regulation Of Wound Healing
Pathways			Antimicrobial peptides
Drugs
Diseases
GWAS		Blood protein levels ( 29875488) Chemerin levels ( 20237162) Diastolic blood pressure ( 26969751) General risk tolerance (MTAG) ( 30643258) Metabolite levels (Dihydroxy docosatrienoic acid) ( 23934736) Perioperative myocardial infarction in coronary artery bypass surgery ( 25948407) Rheumatoid arthritis ( 21452313) Tea consumption ( 31046077)	Body mass index ( 25673413)
Interacting Genes		1 interacting genes: REG3A	6 interacting genes: ANXA3 FN1 MDFI REG1A SDC2 TRHDE
Entrez ID		29953	5068
HPRD ID		09506	01342
Ensembl ID		ENSG00000072657	ENSG00000172016
Uniprot IDs		Q9UKU6	Q06141 Q53S56
PDB IDs			1UV0 2GO0 4MTH
Enriched GO Terms of Interacting Partners?
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