SERTAD1 and PRDM4

Data Source:
BioGRID (two hybrid)

		SERTAD1	PRDM4
Description		SERTA domain containing 1	PR/SET domain 4
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Nucleus Cytoplasm Histone Methyltransferase Complex
	Molecular Function	Protein Binding Transcription Regulator Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Methyltransferase Activity Metal Ion Binding Histone Methyltransferase Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Cell Population Proliferation Positive Regulation Of Transcription By RNA Polymerase II Chromatin-mediated Maintenance Of Transcription	Transcription By RNA Polymerase II Regulation Of Gene Expression Histone H4-R3 Methylation Positive Regulation Of Transcription By RNA Polymerase II
Pathways			p75NTR negatively regulates cell cycle via SC1
Drugs
Diseases
GWAS		Monocyte percentage of white cells ( 32888494) Otitis media ( 27632927) Otitis media (chronic) ( 27632927) Otitis media (recurrent) ( 27632927)	Acne (severe) ( 24927181) Sleep duration ( 30846698)
Interacting Genes		55 interacting genes: ADCY1 ASB8 ATG12 ATXN7L3 BANF2 C1orf109 CCND2 CDK4 CDKN2A CHAF1A CHURC1 CIB3 CINP CKS1B COPB1 CREBBP DENND4A EGLN3 ELOC EP300 FAAP20 FAH FNDC11 GLYCTK HIVEP1 HSPB1 KAT2B KLC4 KLHL42 MVP NEDD4 P4HA3 PATE1 PBX4 PICK1 PIH1D2 POT1 PRDM4 PSORS1C2 RBX1 RCHY1 ROPN1 SEC14L4 SETD7 SFI1 SMAD3 SPEN SSX7 STAT5B SUPT7L TGM2 TLR4 TRIM28 XIAP ZNF410	7 interacting genes: CTNNBL1 EIF4E EMX1 MSRB3 NCS1 SERTAD1 SMAD3
Entrez ID		29950	11108
HPRD ID		15326	10425
Ensembl ID		ENSG00000197019	ENSG00000110851
Uniprot IDs		Q53GC0 Q9UHV2	A0A024RBM7 B3KPI0 Q9UKN5
PDB IDs			2L9Z 3DB5
Enriched GO Terms of Interacting Partners?
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