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PNMA3 and APTX
Data Source:
BioGRID
(two hybrid)
PNMA3
APTX
Description
PNMA family member 3
aprataxin
Image
No pdb structure
GO Annotations
Cellular Component
Nucleolus
Chromatin
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Molecular Function
Nucleic Acid Binding
Protein Binding
Zinc Ion Binding
Chromatin Binding
Damaged DNA Binding
Double-stranded DNA Binding
Single-stranded DNA Binding
Double-stranded RNA Binding
Protein Binding
Phosphoglycolate Phosphatase Activity
Mismatched DNA Binding
DNA 5'-adenosine Monophosphate Hydrolase Activity
Metal Ion Binding
Protein N-terminus Binding
Phosphoprotein Binding
Single-strand Break-containing DNA Binding
Biological Process
Positive Regulation Of Apoptotic Process
Single Strand Break Repair
DNA Ligation
Double-strand Break Repair
Cellular Response To DNA Damage Stimulus
Dephosphorylation
Regulation Of Protein Stability
Response To Hydrogen Peroxide
Nucleic Acid Phosphodiester Bond Hydrolysis
Pathways
Drugs
Diseases
Coenzyme Q10 deficiency
Ataxia with ocular apraxia (AOA), including: Ataxia telangiectasia (AT); Ataxia telangiectasia like disorder (ATLD); Ataxia oculomotor apraxia type 1 (AOA1); Ataxia oculomotor apraxia type 2 (AOA2)
GWAS
Height (
28552196
)
Menopause (age at onset) (
26414677
)
Interacting Genes
12 interacting genes:
APTX
C19orf25
CCDC187
CNNM3
LNX1
PRPF31
RPH3AL
SLC25A37
SMG9
TIGD3
UBQLN2
ZBTB47
18 interacting genes:
CALCOCO1
CEP350
CNTROB
FLAD1
HIVEP1
MAPKBP1
MBP
PARP1
PICK1
PNMA1
PNMA3
SYT17
TP53
TRIM37
TSPYL2
XRCC1
XRCC4
ZNF639
Entrez ID
29944
54840
HPRD ID
06677
05892
Ensembl ID
ENSG00000183837
ENSG00000137074
Uniprot IDs
Q9UL41
Q7Z2E3
PDB IDs
3KT9
4NDF
4NDG
4NDH
4NDI
6CVO
6CVP
6CVQ
6CVR
6CVS
6CVT
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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