CCDC106 and CACNA1S

Data Source:
BioGRID (two hybrid)

		CCDC106	CACNA1S
Description		coiled-coil domain containing 106	calcium voltage-gated channel subunit alpha1 S
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol	Cytoplasm Plasma Membrane Voltage-gated Calcium Channel Complex T-tubule I Band L-type Voltage-gated Calcium Channel Complex
	Molecular Function	Protein Binding	Voltage-gated Calcium Channel Activity Protein Binding Calmodulin Binding High Voltage-gated Calcium Channel Activity Metal Ion Binding
	Biological Process		Calcium Ion Transport Muscle Contraction Regulation Of Ion Transmembrane Transport Cardiac Conduction Calcium Ion Import Calcium Ion Transmembrane Transport Cellular Response To Caffeine
Pathways			NCAM1 interactions
Drugs			Ergocalciferol Enflurane Ranolazine Phenytoin Isradipine Topiramate Nimodipine Nisoldipine Spironolactone Cinnarizine Magnesium sulfate Levomenthol Ethanol Felodipine Nitrendipine Miconazole Nifedipine Amiodarone Mibefradil Dronedarone Clevidipine Nilvadipine Trimebutine Pinaverium Aranidipine Benidipine Cilnidipine Lacidipine Manidipine Butamben Bioallethrin Bioallethrin Fish oil
Diseases			Hypokalemic periodic paralysis (HypoPP)
GWAS			Appendicular lean mass ( 33097823) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cardiac Troponin-T levels ( 31014085) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Crohn's disease ( 28067908) Estimated glomerular filtration rate ( 31152163 31015462 30604766) Glomerular filtration rate (creatinine) ( 28452372) Glomerular filtration rate in non diabetics (creatinine) ( 26831199) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Inflammatory bowel disease ( 28067908) Lymphocyte counts ( 32888494) Lymphocyte percentage of white cells ( 32888494) Monocyte count ( 32888494) Permanent tooth development ( 21931568) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Tooth agenesis ( 29364747) Ulcerative colitis ( 28067908 20228799) Urinary albumin-to-creatinine ratio ( 31511532)
Interacting Genes		26 interacting genes: APP ATF4 CACNA1S CEP19 COPS6 CRMP1 EEF1G EIF1AD ERG28 FAM9B KAT5 KBTBD7 L3MBTL2 LRIF1 MAGEA11 MAGOHB NAA10 NKAPD1 NUTF2 PRPF31 RBM48 RCOR3 SDCBP SETDB1 TP53 UTP14A	8 interacting genes: CCDC106 CYSRT1 MEOX2 PDZD3 REL RIMS2 RYR1 SRI
Entrez ID		29903	779
HPRD ID		09995	00248
Ensembl ID		ENSG00000173581	ENSG00000081248
Uniprot IDs		Q9BWC9	B1ALM3 Q13698
PDB IDs			2VAY 6B27
Enriched GO Terms of Interacting Partners?
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