GUCA1A and BCKDK

Data Source:
BioGRID (proximity labelling technology)

		GUCA1A	BCKDK
Description		guanylate cyclase activator 1A	branched chain keto acid dehydrogenase kinase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Photoreceptor Inner Segment Photoreceptor Disc Membrane Cone Photoreceptor Outer Segment	Mitochondrion Mitochondrial Matrix Mitochondrial Alpha-ketoglutarate Dehydrogenase Complex
	Molecular Function	Calcium Ion Binding Protein Binding Calcium Sensitive Guanylate Cyclase Activator Activity Guanylate Cyclase Regulator Activity	Protein Serine/threonine Kinase Activity Pyruvate Dehydrogenase (acetyl-transferring) Kinase Activity Protein Binding ATP Binding Kinase Activity [3-methyl-2-oxobutanoate Dehydrogenase (acetyl-transferring)] Kinase Activity
	Biological Process	Signal Transduction Visual Perception Phototransduction Positive Regulation Of CGMP-mediated Signaling Regulation Of Rhodopsin Mediated Signaling Pathway Positive Regulation Of Guanylate Cyclase Activity Cellular Response To Calcium Ion	Protein Phosphorylation Cellular Amino Acid Catabolic Process Branched-chain Amino Acid Catabolic Process Regulation Of Glucose Metabolic Process Phosphorylation
Pathways		Inactivation, recovery and regulation of the phototransduction cascade	Branched-chain amino acid catabolism
Drugs		Myristic acid	Adenosine 5'-[gamma-thio]triphosphate
Diseases		Cone-rod dystrophy and cone dystrophy, including: Cone-rod dystrophy (CORD); Cone dystrophy (COD); Retinal cone dystrophy (RCD)
GWAS		Spatial processing ( 31596458)	Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Parkinson's disease ( 25064009) Systolic blood pressure ( 31928498) Triglyceride levels ( 31928498) Waist circumference ( 31928498)
Interacting Genes		9 interacting genes: AGR2 C1QTNF5 DDIT4L DEFB118 GSC2 GUCY2D HSPB1 KATNAL1 PRKAR1B	8 interacting genes: APP EPS8 FBXO7 LSM8 NR5A2 SPTA1 STAT3 TRAF4
Entrez ID		2978	10295
HPRD ID		02648	12523
Ensembl ID		ENSG00000048545	ENSG00000103507
Uniprot IDs		B2R9P6 P43080	A0A024QZA9 O14874
PDB IDs
Enriched GO Terms of Interacting Partners?
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