GSTA1 and GSTA2

Data Source:
HPRD (in vitro)

		GSTA1	GSTA2
Description		glutathione S-transferase alpha 1	glutathione S-transferase alpha 2
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GO Annotations	Cellular Component	Cytosol Extracellular Exosome	Cytosol Extracellular Exosome
	Molecular Function	Glutathione Transferase Activity Glutathione Peroxidase Activity Steroid Delta-isomerase Activity Fatty Acid Binding	Glutathione Transferase Activity Protein Binding
	Biological Process	Prostaglandin Metabolic Process Glutathione Metabolic Process Xenobiotic Metabolic Process Epithelial Cell Differentiation Linoleic Acid Metabolic Process Cellular Oxidant Detoxification Glutathione Derivative Biosynthetic Process	Glutathione Metabolic Process Xenobiotic Metabolic Process Epithelial Cell Differentiation Interleukin-12-mediated Signaling Pathway Glutathione Derivative Biosynthetic Process
Pathways		Glutathione conjugation Heme degradation	Glutathione conjugation Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs		Glutathione S-Hydroxycysteine 2-Hydroxyethyl Disulfide N-(4-Aminobutanoyl)-S-(4-methoxybenzyl)-L-cysteinylglycine Glutathione sulfonic acid Glutathione disulfide S-benzylglutathione S-Hexylglutathione Hypericin	Glutathione Chloroquine Glutathione disulfide
Diseases
GWAS		Blood protein levels ( 29875488) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) Platelet count ( 32888494 27863252) Plateletcrit ( 32888494 27863252)	Apolipoprotein A1 levels ( 32203549) Estimated glomerular filtration rate ( 31152163) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Hemoglobin levels ( 32327693) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Red cell distribution width ( 32888494) Triglyceride levels ( 32203549 30698716) Triglyceride levels in current drinkers ( 30698716) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
Interacting Genes		7 interacting genes: APP GSTA2 LSM3 PPP2CB RPAIN ST3GAL1 YWHAE	3 interacting genes: GSTA1 GSTA4 GSTA5
Entrez ID		2938	2939
HPRD ID		00708	00709
Ensembl ID		ENSG00000243955	ENSG00000244067
Uniprot IDs		A0A140VJK4 B7Z1F9 P08263	A0A140VKE2 A8K987 P09210
PDB IDs		1GSD 1GSE 1GSF 1GUH 1K3L 1K3O 1K3Y 1LBK 1PKW 1PKZ 1PL1 1PL2 1USB 1XWG 1YDK 2R3X 2R6K 3I69 3I6A 3IK9 3KTL 3L0H 3Q74 3U6V 3ZFB 3ZFL 4HJ2 5JCU 5LCZ 5LD0 6ATO 6ATP 6ATQ 6ATR 6YAW	1AGS 2VCT 2WJU 4ACS
Enriched GO Terms of Interacting Partners?
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